KLF10, Kruppel like factor 10

KLF10, Kruppel like factor 10

• This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

• Gene Synonyms (Krueppel-like factor 10, TGFB-inducible early growth response protein 1, early growth response-alpha, transforming growth factor-beta-inducible early growth response protein 1, zinc finger transcription factor TIEG, EGR-alpha, EGRA, TIEG, TIEG1,)
• NCBI Gene ID: 7071
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q13118
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Kruppel like factor 10 interacts with:

• BOP1 ribosomal biogenesis factor
  F-box and WD repeat domain containing 7
  itchy E3 ubiquitin protein ligase
  leukocyte receptor cluster member 1
  lysine acetyltransferase 2B
  lysine demethylase 5B
  ribosomal protein L14
  SIN3 transcription regulator family member A
  splicing factor 3b subunit 3
  tensin 1
  tyrosine kinase 2
  zinc finger protein 512B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.