SNCAIP, synuclein alpha interacting protein

SNCAIP, synuclein alpha interacting protein

• This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

• Gene Synonyms (synphilin-1, SYPH1, Sph1,)
• NCBI Gene ID: 9627
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y6H5
  UNIPROT ID#>>Q6L983
  UNIPROT ID#>>B7Z616
  UNIPROT ID#>>Q6L981
  UNIPROT ID#>>B7Z995
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

synuclein alpha interacting protein interacts with:

• ariadne RBR E3 ubiquitin protein ligase 1
  chromosome 11 open reading frame 58
  guided entry of tail-anchored proteins factor 4
  heat shock protein 5
  homocysteine inducible ER protein with ubiquitin like domain 1
  negative regulator of ubiquitin like proteins 1
  nudix hydrolase 21
  periphilin 1
  periphilin 1
  PTEN induced kinase 1
  ring finger protein 19A, RBR E3 ubiquitin protein ligase
  SH2 domain containing 3C
  synuclein alpha interacting protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.