TAF15, TATA-box binding protein associated factor 15

TAF15, TATA-box binding protein associated factor 15

• This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]

• Gene Synonyms (TATA-binding protein-associated factor 2N, RBP56/CSMF fusion, TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa, TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56), TATA box-binding protein-associated factor 2N (RNA-binding protein 56), TBP-associated factor 15, Npl3, RBP56, TAF2N, TAFII68,)
• NCBI Gene ID: 8148
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q92804
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TATA-box binding protein associated factor 15 interacts with:

• acetyl-CoA acyltransferase 2
  agrin
  anoctamin 7
  apoptotic chromatin condensation inducer 1
  aquarius intron-binding spliceosomal factor
  arginine and serine rich coiled-coil 1
  ariadne RBR E3 ubiquitin protein ligase 2
  aspartyl aminopeptidase
  AT-rich interaction domain 1A
  BCL2 associated transcription factor 1
  calcium homeostasis endoplasmic reticulum protein
  calmodulin like 5
  caspase 14
  cell cycle and apoptosis regulator 2
  cell division cycle and apoptosis regulator 1
  centrosomal protein 55
  contactin associated protein 1
  COP9 signalosome subunit 5
  COP9 signalosome subunit 6
  cullin 1
  cullin 2
  cullin 3
  cullin 4A
  cullin 4B
  cullin 7
  cullin associated and neddylation dissociated 1
  DEAD-box helicase 17
  DEAD-box helicase 23
  DEAD-box helicase 42
  DEAD-box helicase 46
  decapping enzyme, scavenger
  defective in cullin neddylation 1 domain containing 1
  elongation factor Tu GTP binding domain containing 2
  embryonic ectoderm development
  family with sequence similarity 120A
  fused in sarcoma
  gasdermin A
  gem nuclear organelle associated protein 5
  H2A clustered histone 20
  H3 clustered histone 1
  H3.4 histone
  H4 clustered histone 1
  H4 clustered histone 14
  heterogeneous nuclear ribonucleoprotein A3
  heterogeneous nuclear ribonucleoprotein C like 1
  heterogeneous nuclear ribonucleoprotein R
  heterogeneous nuclear ribonucleoprotein U like 1
  HEXIM P-TEFb complex subunit 1
  HIV-1 Tat specific factor 1
  kelch like family member 8
  La ribonucleoprotein 1, translational regulator
  La ribonucleoprotein 7, transcriptional regulator
  lysine acetyltransferase 2B
  matrin 3
  mediator complex subunit 12
  mediator complex subunit 26
  methylphosphate capping enzyme
  mitogen-activated protein kinase 13
  Mtr4 exosome RNA helicase
  obscurin like cytoskeletal adaptor 1
  PAX3 and PAX7 binding protein 1
  pleckstrin homology domain containing A4
  poly(A) binding protein cytoplasmic 1
  poly(A) binding protein cytoplasmic 4
  potassium channel modulatory factor 1
  POTE ankyrin domain family member F
  pre-mRNA processing factor 19
  pre-mRNA processing factor 4B
  pre-mRNA processing factor 6
  prohibitin 2
  protein arginine methyltransferase 8
  protein kinase D2
  ring finger and CCCH-type domains 2
  ring finger protein 168
  ring finger protein 181
  RNA binding motif protein 10
  RNA binding motif protein 17
  RNA binding motif protein 25
  RNA binding motif protein 39
  RuvB like AAA ATPase 1
  SAFB like transcription modulator
  SAP30 binding protein
  scaffold attachment factor B2
  serine and arginine-rich splicing factor 1
  serrate, RNA effector molecule
  Sin3A associated protein 18
  sirtuin 7
  small nuclear ribonucleoprotein 70 (U1)
  small nuclear ribonucleoprotein U5 subunit 200
  small nuclear ribonucleoprotein U5 subunit 40
  SMU1 DNA replication regulator and spliceosomal factor
  splicing factor 3a subunit 1
  splicing factor 3a subunit 3
  splicing factor 3b subunit 1
  splicing factor 3b subunit 2
  splicing factor 3b subunit 3
  SR-related CTD associated factor 11
  suppressor of cytokine signaling 2
  suppressor of cytokine signaling 6
  SUZ12 polycomb repressive complex 2 subunit
  synaptotagmin binding cytoplasmic RNA interacting protein
  target of EGR1, exonuclease
  TATA-box binding protein associated factor 15
  TATA-box binding protein associated factor 15
  testis expressed 2
  tet methylcytosine dioxygenase 2
  THO complex 1
  THO complex 2
  THO complex 3
  THO complex 5
  THO complex 6
  thyroid hormone receptor associated protein 3
  transmembrane p24 trafficking protein 9
  tripartite motif containing 28
  tuftelin interacting protein 11
  U2 small nuclear RNA auxiliary factor 2
  U2 snRNP associated SURP domain containing
  ubiquitin specific peptidase 14
  WD repeat domain 77
  WW domain containing E3 ubiquitin protein ligase 2
  XPA binding protein 2
  zinc finger CCCH-type containing 18
  zinc finger CCHC-type containing 8
  zinc finger FYVE-type containing 21
  zinc finger protein 326
  zinc finger protein 384
  zinc finger protein 609
  zymogen granule protein 16B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.