RBM39, RNA binding motif protein 39

RBM39, RNA binding motif protein 39

• This gene encodes a member of the U2AF65 family of proteins. The encoded protein is found in the nucleus, where it co-localizes with core spliceosomal proteins. It has been shown to play a role in both steroid hormone receptor-mediated transcription and alternative splicing, and it is also a transcriptional coregulator of the viral oncoprotein v-Rel. Multiple transcript variants have been observed for this gene. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Aug 2011]

• Gene Synonyms (RNA-binding protein 39, CAPER alpha, RNA-binding region (RNP1, RRM) containing 2, coactivator of activating protein-1 and estrogen receptors, epididymis secretory sperm binding protein, functional spliceosome-associated protein 59, hepatocellular carcinoma protein 1, splicing factor HCC1, CAPER, CAPERalpha, FSAP59, HCC1, RNPC2,)
• NCBI Gene ID: 9584
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DRA0
  UNIPROT ID#>>Q6N037
  UNIPROT ID#>>E1P5S2
  UNIPROT ID#>>Q14498
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RNA binding motif protein 39 interacts with:

• AAR2 splicing factor
  activation induced cytidine deaminase
  activator of HSP90 ATPase activity 1
  adenylate kinase 8
  ADP ribosylation factor like GTPase 6 interacting protein 4
  apoptotic chromatin condensation inducer 1
  ariadne RBR E3 ubiquitin protein ligase 2
  BCAS2 pre-mRNA processing factor
  bromodomain containing 7
  BTB and CNC homology 1, basic leucine zipper transcription factor 1
  BTG3 associated nuclear protein
  calcium homeostasis endoplasmic reticulum protein
  cap methyltransferase 1
  catenin beta like 1
  cereblon
  clusterin associated protein 1
  COP9 signalosome subunit 5
  cullin 7
  cullin associated and neddylation dissociated 1
  cyclin dependent kinase 12
  DDB1 and CUL4 associated factor 15
  family with sequence similarity 200 member A
  F-box and WD repeat domain containing 7
  F-box protein 7
  G-patch domain containing 1
  HECT domain E3 ubiquitin protein ligase 1
  histone deacetylase 5
  homeobox and leucine zipper encoding
  INO80 complex subunit B
  integrin alpha FG-GAP repeat containing 1
  interferon regulatory factor 2 binding protein 2
  interferon regulatory factor 2 binding protein like
  jumonji domain containing 6, arginine demethylase and lysine hydroxylase
  keratin associated protein 12-2
  KH domain containing 4, pre-mRNA splicing factor
  KH RNA binding domain containing, signal transduction associated 2
  Kin17 DNA and RNA binding protein
  L3MBTL histone methyl-lysine binding protein 1
  La ribonucleoprotein 7, transcriptional regulator
  leucine aminopeptidase 3
  LUC7 like 2, pre-mRNA splicing factor
  lysine methyltransferase 2E (inactive)
  mediator complex subunit 9
  mediator of DNA damage checkpoint 1
  methylphosphate capping enzyme
  microcephalin 1
  mitochondrial carrier 2
  NFKB activating protein
  ninein like
  NKAP domain containing 1
  nuclear receptor coactivator 6
  nuclear RNA export factor 1
  obscurin like cytoskeletal adaptor 1
  peptidylprolyl isomerase E
  pleckstrin homology domain containing A4
  PNN interacting serine and arginine rich protein
  poly(rC) binding protein 3
  potassium channel tetramerization domain containing 10
  potassium channel, subfamily K, member 1
  POU class 6 homeobox 2
  PR/SET domain 16
  pre-mRNA processing factor 19
  pre-mRNA processing factor 38A
  pre-mRNA processing factor 40 homolog A
  proteasome activator subunit 3
  PTEN induced kinase 1
  RALY heterogeneous nuclear ribonucleoprotein
  RBM14-RBM4 readthrough
  ribosomal RNA processing 7 homolog A
  ribosome biogenesis regulator 1 homolog
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  RIO kinase 1
  RNA binding motif protein 14
  RNA binding motif protein 23
  RNA binding motif protein 25
  RNA binding protein with serine rich domain 1
  SAP30 binding protein
  SEC16 homolog A, endoplasmic reticulum export factor
  serine and arginine repetitive matrix 1
  serine/arginine repetitive matrix 2
  serine/arginine repetitive matrix 4
  Sin3A associated protein 18
  sirtuin 7
  small nuclear ribonucleoprotein U5 subunit 200
  SMU1 DNA replication regulator and spliceosomal factor
  SNW domain containing 1
  splicing factor 3a, subunit 1
  splicing factor 3b subunit 1
  splicing factor 3b subunit 4
  splicing regulatory glutamic acid and lysine rich protein 1
  SprT-like N-terminal domain
  SREK1 interacting protein 1
  SRSF protein kinase 3
  staphylococcal nuclease and tudor domain containing 1
  SUZ12 polycomb repressive complex 2 subunit
  TAR DNA binding protein
  target of EGR1, exonuclease
  tetratricopeptide repeat domain 14
  THAP domain containing 1
  tripartite motif containing 14
  tRNA methyltransferase subunit 11-2
  U2 small nuclear RNA auxiliary factor 2
  ubiquitin specific peptidase 39
  UTP14A small subunit processome component
  WD repeat domain 77
  WW domain containing E3 ubiquitin protein ligase 2
  WW domain containing oxidoreductase
  Yes1 associated transcriptional regulator
  zinc finger and BTB domain containing 38
  zinc finger and BTB domain containing 7A
  zinc finger CCHC-type containing 10
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.