NCOA6, nuclear receptor coactivator 6

NCOA6, nuclear receptor coactivator 6

• The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. This protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]

• Gene Synonyms (AIB3, ASC2, NRC, PRIP, RAP250, TRBP, nuclear receptor coactivator 6, NRC RAP250, PPAR-interacting protein, activating signal cointegrator-2, amplified in breast cancer protein 3, amplified in breast cancer-3 protein, cancer-amplified transcriptional coactivator ASC-2, nuclear receptor coactivator RAP250, nuclear receptor-activating protein, 250 kDa, peroxisome proliferator-activated receptor interacting protein, thyroid hormone receptor binding protein,)
• NCBI Gene ID: 23054
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q14686
  UNIPROT ID#>>F6M2K3
  UNIPROT ID#>>F6M2K2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nuclear receptor coactivator 6 interacts with:

• activating signal cointegrator 1 complex subunit 1
  dpy-30 histone methyltransferase complex regulatory subunit
  formin homology 2 domain containing 1
  glutamate receptor interacting protein 1
  H3 clustered histone 14
  lysine methyltransferase 2C
  MAF bZIP transcription factor A
  mediator complex subunit 15
  nuclear receptor coactivator 6
  PAXIP1 associated glutamate rich protein 1
  RNA binding motif protein 39
  trimethylguanosine synthase 1
  trinucleotide repeat containing adaptor 6A
  vir like m6A methyltransferase associated
  zinc finger protein 335

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.