SF3A1, splicing factor 3a subunit 1

SF3A1, splicing factor 3a subunit 1

• This gene encodes a subunit of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer is a component of the mature U2 small nuclear ribonucleoprotein particle (snRNP). U2 small nuclear ribonucleoproteins play a critical role in spliceosome assembly and pre-mRNA splicing. [provided by RefSeq, Aug 2014]

• Gene Synonyms (PRP21, PRPF21, SAP114, SF3A120, splicing factor 3A subunit 1, SAP 114, pre-mRNA processing 21, pre-mRNA splicing factor SF3a (120 kDa subunit), spliceosome-associated protein 114, splicing factor 3 subunit 1, splicing factor 3a, subunit 1, 120kD, splicing factor 3a, subunit 1, 120kDa,)
• NCBI Gene ID: 10291
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R1K8
  UNIPROT ID#>>Q15459
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

splicing factor 3a subunit 1 interacts with:

• AAR2 splicing factor
  apoptotic chromatin condensation inducer 1
  BRCA1/BRCA2-containing complex subunit 3
  CD2 cytoplasmic tail binding protein 2
  coiled-coil domain containing 97
  cullin associated and neddylation dissociated 1
  DEAD-box helicase 17
  DEAD-box helicase 42
  forkhead box Q1
  formin binding protein 1
  formin binding protein 1 like
  GTPase activating protein and VPS9 domains 1
  HEXIM P-TEFb complex subunit 1
  histone deacetylase 11
  ISY1 splicing factor homolog
  ISY1-RAB43 readthrough
  jun B proto-oncogene
  La ribonucleoprotein 7, transcriptional regulator
  leucine rich repeat kinase 2
  LUC7 like 2, pre-mRNA splicing factor
  microtubule associated protein 1 light chain 3 gamma
  M-phase phosphoprotein 9
  Mtr4 exosome RNA helicase
  NKAP domain containing 1
  nuclear RNA export factor 1
  obscurin like cytoskeletal adaptor 1
  PAT1 homolog 1, processing body mRNA decay factor
  peptidylprolyl isomerase E
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  poly(A) binding protein cytoplasmic 1
  pre-mRNA processing factor 19
  pre-mRNA processing factor 31
  pre-mRNA processing factor 40 homolog A
  pre-mRNA processing factor 6
  pre-mRNA processing factor 8
  protein phosphatase 4 regulatory subunit 2
  protein phosphatase 4 regulatory subunit 3A
  PTEN induced kinase 1
  quinolinate phosphoribosyltransferase
  RALY RNA binding protein like
  RNA binding fox-1 homolog 2
  RNA binding motif protein 12B
  RNA binding motif protein 14
  RNA binding motif protein 17
  RNA binding motif protein X-linked
  serine/arginine repetitive matrix 2
  sirtuin 7
  SMAD specific E3 ubiquitin protein ligase 1
  small nuclear ribonucleoprotein U4/U6.U5 subunit 27
  small nuclear ribonucleoprotein U5 subunit 200
  SNW domain containing 1
  splicing factor 3a subunit 3
  splicing factor 3a, subunit 1
  splicing factor 3b subunit 1
  splicing factor 3b subunit 3
  SPT16 homolog, facilitates chromatin remodeling subunit
  staphylococcal nuclease and tudor domain containing 1
  SUZ12 polycomb repressive complex 2 subunit
  TEPSIN adaptor related protein complex 4 accessory protein
  testis specific serine kinase substrate
  transcription elongation regulator 1
  transformer 2 alpha homolog
  tripartite motif containing 55
  tRNA methyltransferase 2 homolog A
  tRNA methyltransferase subunit 11-2
  U2 small nuclear RNA auxiliary factor 2
  U2 snRNP associated SURP domain containing
  ubiquitin specific peptidase 30
  ubiquitin specific peptidase 39
  UTP14A small subunit processome component
  vasorin
  vir like m6A methyltransferase associated
  WD repeat domain 77
  WW domain binding protein 4
  WW domain containing oxidoreductase
  XPA binding protein 2
  zinc finger and BTB domain containing 1
  zinc finger CCCH-type containing 18
  zinc finger matrin-type 3
  zinc finger protein 326
  zinc finger protein 830

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.