SNRNP27, small nuclear ribonucleoprotein U4/U6.U5 subunit 27

SNRNP27, small nuclear ribonucleoprotein U4/U6.U5 subunit 27

• This gene encodes a serine/arginine-rich (SR) protein. SR proteins play important roles in pre-mRNA splicing by facilitating the recognition and selection of splice sites. The encoded protein associates with the 25S U4/U6.U5 tri-snRNP, a major component of the U2-type spiceosome. The expression of this gene may be altered in cells infected with the human T-cell lymphotropic virus type 1 (HTLV-1) retrovirus. A pseudogene of this gene is located on the long arm of chromosome 5. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]

• Gene Synonyms (27K, RY1, U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein, U4/U6.U5 tri-snRNP-associated 27 kDa protein, U4/U6.U5 tri-snRNP-associated protein 3, U4/U6.U5-27K, putative nucleic acid binding protein RY-1, small nuclear ribonucleoprotein 27kDa (U4/U6.U5), small nuclear ribonucleoprotein, U4/U6.U5 27kDa subunit,)
• NCBI Gene ID: 11017
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8WVK2
  UNIPROT ID#>>A8K513
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

small nuclear ribonucleoprotein U4/U6.U5 subunit 27 interacts with:

• acidic residue methyltransferase 1
  arginine and glutamate rich 1
  atlastin GTPase 2
  caspase recruitment domain family member 19
  catenin beta like 1
  coiled-coil domain containing 51
  cysteine and histidine rich domain containing 1
  DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
  eukaryotic translation initiation factor 2A
  glutamine rich 1
  HDGF like 2
  heat shock protein family A (Hsp70) member 14
  HECT domain E3 ubiquitin protein ligase 1
  hes related family bHLH transcription factor with YRPW motif 1
  high mobility group nucleosome binding domain 5
  ILK associated serine/threonine phosphatase
  LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
  LUC7 like 2, pre-mRNA splicing factor
  MCTS1 re-initiation and release factor
  metaxin 3
  methylphosphate capping enzyme
  N-alpha-acetyltransferase 15, NatA auxiliary subunit
  N-alpha-acetyltransferase 50, NatE catalytic subunit
  nucleoporin 35
  OTU deubiquitinase, ubiquitin aldehyde binding 1
  PDZ binding kinase
  peptidylprolyl isomerase like 4
  pre-mRNA processing factor 8
  programmed cell death 10
  proline rich coiled-coil 1
  protein phosphatase 4 regulatory subunit 3A
  regulation of nuclear pre-mRNA domain containing 1A
  regulation of nuclear pre-mRNA domain containing 1B
  RNA binding motif protein 42
  SBDS ribosome maturation factor
  SEC23 interacting protein
  secretion associated Ras related GTPase 1B
  serine/threonine kinase 26
  sorting nexin 6
  synapse associated protein 1
  taxilin alpha
  taxilin gamma
  triokinase and FMN cyclase
  ubiquitin conjugating enzyme E2 T
  ubiquitin like modifier activating enzyme 6
  WD repeat domain 5B
  zinc finger CCCH-type and G-patch domain containing

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.