BCLAF1, BCL2 associated transcription factor 1

BCLAF1, BCL2 associated transcription factor 1

• This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (bcl-2-associated transcription factor 1, BCLAF1 and THRAP3 family member 1, BTF, bK211L9.1,)
• NCBI Gene ID: 9774
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NYF8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

BCL2 associated transcription factor 1 interacts with:

• activator of HSP90 ATPase activity 1
  alkB homolog 3, alpha-ketoglutarate dependent dioxygenase
  Aly/REF export factor
  ankyrin repeat and SOCS box containing 18
  ankyrin repeat and SOCS box containing 3
  bromodomain containing 7
  BTB domain containing 8
  cap methyltransferase 1
  CDKN2A interacting protein N-terminal like
  cell division cycle 6
  chromatin target of PRMT1
  chromobox 8
  coenzyme Q2, polyprenyltransferase
  cullin 7
  cullin associated and neddylation dissociated 1
  cyclin dependent kinase 12
  DENN/MADD domain containing 6A
  DNA polymerase delta interacting protein 3
  ERH mRNA splicing and mitosis factor
  four and a half LIM domains 1
  glutamate rich WD repeat containing 1
  histone deacetylase 11
  LEM domain containing 3
  leucine zipper protein 4
  LUC7 like
  LUC7 like 2, pre-mRNA splicing factor
  MAD2 mitotic arrest deficient-like 1
  matrin 3
  mediator complex subunit 4
  mitochondrial carrier 2
  myosin heavy chain 7B
  Nanog homeobox
  NHL repeat containing 2
  nuclear RNA export factor 1
  NUMB endocytic adaptor protein
  obscurin like cytoskeletal adaptor 1
  Parkinsonism associated deglycase
  PAX interacting protein 1
  periphilin 1
  pleckstrin homology domain containing A4
  poly(A) specific ribonuclease subunit PAN2
  proteasome (prosome, macropain) subunit, beta type 5
  proteasome activator subunit 3
  protein arginine methyltransferase 8
  protein kinase, AMP-activated, alpha 1 catalytic subunit
  PTEN induced kinase 1
  RAD18 E3 ubiquitin protein ligase
  RBMX like 1
  rhomboid domain containing 1
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  ring finger protein 31
  ring-box 1
  serine and arginine repetitive matrix 1
  serine and arginine-rich splicing factor 1
  Smad nuclear interacting protein 1
  SMAD specific E3 ubiquitin protein ligase 1
  solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
  spen family transcriptional repressor
  spindle apparatus coiled-coil protein 1
  spindlin 1
  SUZ12 polycomb repressive complex 2 subunit
  TAR DNA binding protein
  THO complex 1
  THO complex 2
  THO complex 3
  THO complex 6
  THO complex 7
  thyroid hormone receptor associated protein 3
  timeless interacting protein
  TNFAIP3 interacting protein 2
  U2 small nuclear RNA auxiliary factor 2
  ubiquitin like with PHD and ring finger domains 2
  unk zinc finger
  USO1 vesicle docking factor
  vir like m6A methyltransferase associated
  VRK serine/threonine kinase 3
  zinc finger and BTB domain containing 1
  zinc finger CCCH-type containing 11A
  zinc finger MIZ-type containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.