ALYREF, Aly/REF export factor

ALYREF, Aly/REF export factor

• The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins. [provided by RefSeq, Jul 2008]

• Gene Synonyms (THO complex subunit 4, THO complex 4, ally of AML-1 and LEF-1, bZIP enhancing factor, bZIP-enhancing factor BEF, tho4, transcriptional coactivator Aly/REF, ALY, ALY/REF, BEF, REF, THOC4,)
• NCBI Gene ID: 10189
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86V81
  UNIPROT ID#>>E9PB61
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Aly/REF export factor interacts with:

• 5'-3' exoribonuclease 1
  Aly/REF export factor
  anterior gradient 2, protein disulphide isomerase family member
  apoptotic chromatin condensation inducer 1
  ariadne RBR E3 ubiquitin protein ligase 2
  autophagy related 16 like 1
  bromodomain containing 7
  cap methyltransferase 1
  centrosomal protein 250
  chromobox 8
  coenzyme Q2, polyprenyltransferase
  coiled-coil-helix-coiled-coil-helix domain containing 2
  COP9 signalosome subunit 5
  cullin associated and neddylation dissociated 1
  DExD-box helicase 39A
  DISC1 scaffold protein
  DNA polymerase delta interacting protein 3
  DOT1 like histone lysine methyltransferase
  Era like 12S mitochondrial rRNA chaperone 1
  ERH mRNA splicing and mitosis factor
  family with sequence similarity 120A
  F-box protein 6
  FGFR1 oncogene partner 2
  HEXIM P-TEFb complex subunit 1
  immunoglobulin superfamily member 8
  INO80 complex subunit B
  integrin alpha FG-GAP repeat containing 1
  interacts with SUPT6H, CTD assembly factor 1
  Kin17 DNA and RNA binding protein
  kinesin family member 1C
  La ribonucleoprotein 7, transcriptional regulator
  leucine zipper protein 4
  LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
  LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
  LSM8 homolog, U6 small nuclear RNA associated
  lymphoid enhancer binding factor 1
  methylphosphate capping enzyme
  mex-3 RNA binding family member C
  mitochondrial ribosomal protein L1
  mitochondrial ribosomal protein L11
  mitochondrial ribosomal protein L15
  mitochondrial ribosomal protein L18
  mitochondrial ribosomal protein L28
  mitochondrial ribosomal protein L3
  mitochondrial ribosomal protein L30
  mitochondrial ribosomal protein L43
  mitochondrial ribosomal protein L45
  mitochondrial ribosomal protein L50
  mitochondrial ribosomal protein L51
  mitochondrial ribosomal protein L52
  mitochondrial ribosomal protein L9
  mitochondrial ribosomal protein S15
  mitochondrial ribosomal protein S16
  mitochondrial ribosomal protein S18B
  mitochondrial ribosomal protein S18C
  mitochondrial ribosomal protein S2
  mitochondrial ribosomal protein S22
  mitochondrial ribosomal protein S23
  mitochondrial ribosomal protein S25
  mitochondrial ribosomal protein S26
  mitochondrial ribosomal protein S27
  mitochondrial ribosomal protein S28
  mitochondrial ribosomal protein S31
  mitochondrial ribosomal protein S34
  mitochondrial ribosomal protein S35
  mitochondrial ribosomal protein S5
  mitochondrial ribosomal protein S6
  mitochondrial ribosomal protein S7
  mitochondrial ribosomal protein S9
  N-alpha-acetyltransferase 16, NatA auxiliary subunit
  Nanog homeobox
  NEDD1 gamma-tubulin ring complex targeting factor
  nuclear cap binding subunit 3
  nuclear RNA export factor 1
  Obg like ATPase 1
  obscurin like cytoskeletal adaptor 1
  Parkinsonism associated deglycase
  PAX interacting protein 1
  PCF11 cleavage and polyadenylation factor subunit
  pentatricopeptide repeat domain 3
  peptidylprolyl isomerase H
  pleckstrin homology domain containing A4
  poly(A) binding protein cytoplasmic 1
  pre-mRNA processing factor 8
  protein arginine methyltransferase 8
  PX domain containing serine/threonine kinase like
  RAD18 E3 ubiquitin protein ligase
  ribosomal protein L26 like 1
  ribosomal RNA processing 1 homolog B (S. cerevisiae)
  ribosomal RNA processing 1B
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  ring finger protein 123
  ring finger protein 31
  RNA binding motif protein 15
  RNA binding motif protein 15B
  RNA binding motif protein 17
  RNA binding motif protein 34
  SCY1 like pseudokinase 2
  serine and arginine repetitive matrix 1
  serine/arginine repetitive matrix 2
  serrate, RNA effector molecule
  sirtuin 7
  splicing factor 3b subunit 4
  SUZ12 polycomb repressive complex 2 subunit
  THO complex 2
  THO complex 3
  THO complex 6
  THO complex 7
  TNFAIP3 interacting protein 2
  U2 small nuclear RNA auxiliary factor 2
  ubiquitin like modifier activating enzyme 5
  UDP-glucose glycoprotein glucosyltransferase 1
  UPF3A regulator of nonsense mediated mRNA decay
  vir like m6A methyltransferase associated
  VRK serine/threonine kinase 3
  WD repeat domain 35
  WD repeat domain 77
  WW domain containing E3 ubiquitin protein ligase 2
  zinc finger CCCH-type containing 13
  zinc finger CCCH-type containing, antiviral 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.