RPS6KB2, ribosomal protein S6 kinase B2

RPS6KB2, ribosomal protein S6 kinase B2

• This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq, Jan 2015]

• Gene Synonyms (ribosomal protein S6 kinase beta-2, 70 kDa ribosomal protein S6 kinase 2, P70S6K2, S6 kinase-related kinase, S6K-beta, S6K-beta-2, p70 S6 kinase beta, p70 S6K-beta, p70 S6KB, p70 ribosomal S6 kinase beta, p70-S6K 2, ribosomal protein S6 kinase, 70kDa, polypeptide 2, serine/threonine-protein kinase 14 beta, serine/threonine-protein kinase 14B, KLS, P70-beta, P70-beta-1, P70-beta-2, S6K-beta2, S6K2, S6KB, S6KI(2), S6Kbeta, SRK, STK14B, p70(S6K)-beta, p70S6Kb,)
• NCBI Gene ID: 6199
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UBS0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ribosomal protein S6 kinase B2 interacts with:

• ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase
  ankyrin repeat and MYND domain containing 2
  apoptosis inducing factor mitochondria associated 1
  BAG cochaperone 2
  BUD23 rRNA methyltransferase and ribosome maturation factor
  cell division cycle 37, HSP90 cochaperone
  cell division cycle 45
  chaperonin containing TCP1 subunit 2
  chaperonin containing TCP1 subunit 3
  chaperonin containing TCP1 subunit 4
  chaperonin containing TCP1 subunit 5
  chaperonin containing TCP1 subunit 7
  chaperonin containing TCP1 subunit 8
  Coenzyme A synthase
  coiled-coil domain containing 124
  DEAD-box helicase 17
  DExD-box helicase 21
  DNA polymerase delta interacting protein 3
  DnaJ heat shock protein family (Hsp40) member A2
  DnaJ heat shock protein family (Hsp40) member C7
  eukaryotic elongation factor 2 kinase
  eukaryotic translation initiation factor 2 subunit beta
  eukaryotic translation initiation factor 3 subunit B
  F-box protein 25
  FKBP prolyl isomerase 8
  G3BP stress granule assembly factor 1
  growth differentiation factor 5
  heat shock protein family A (Hsp70) member 14
  heat shock protein family A (Hsp70) member 4 like
  heat shock protein family H (Hsp110) member 1
  histone acetyltransferase 1
  importin 7
  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
  insulin like growth factor 2 mRNA binding protein 1
  IQ motif containing GTPase activating protein 1
  leucine rich pentatricopeptide repeat containing
  leucine rich repeat containing 15
  leucine rich repeat kinase 2
  LTV1 ribosome biogenesis factor
  lysine acetyltransferase 2B
  MAGE family member D1
  MAGE family member D2
  mitochondrial ribosomal protein S22
  mitogen-activated protein kinase 8 interacting protein 2
  NEDD4 like E3 ubiquitin protein ligase
  nuclear distribution C, dynein complex regulator
  nuclear RNA export factor 1
  paraspeckle component 1
  phosphoglycerate dehydrogenase
  poly(A) binding protein cytoplasmic 1
  programmed cell death 4
  prostaglandin E synthase 3
  protein phosphatase 6 regulatory subunit 1
  protein phosphatase 6 regulatory subunit 3
  ribosomal protein L14
  ribosomal protein L22 like 1
  ribosomal protein S13
  ribosomal protein S14
  ribosomal protein S15a
  ribosomal protein S17
  ribosomal protein S18
  ribosomal protein S19
  ribosomal protein S24
  ribosomal protein S25
  ribosomal protein S26
  ribosomal protein S7
  ribosomal protein S8
  RNA 2',3'-cyclic phosphate and 5'-OH ligase
  RuvB like AAA ATPase 1
  RuvB like AAA ATPase 2
  serine and arginine rich splicing factor 2
  SERPINE1 mRNA binding protein 1
  SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
  shroom family member 3
  signal sequence receptor subunit 1
  SIN3-HDAC complex associated factor
  small nuclear ribonucleoprotein polypeptide E
  small nuclear ribonucleoprotein polypeptides B and B1
  solute carrier family 3 member 2
  spermatid perinuclear RNA binding protein
  spleen associated tyrosine kinase
  splicing factor proline and glutamine rich
  SRC proto-oncogene, non-receptor tyrosine kinase
  SRSF protein kinase 1
  STIP1 homology and U-box containing protein 1
  TATA-box binding protein associated factor 15
  t-complex 1
  transcription factor A, mitochondrial
  translocase of inner mitochondrial membrane 50
  Tu translation elongation factor, mitochondrial
  tubulin alpha 1b
  tubulin alpha 1c
  tubulin beta 3 class III
  tubulin beta 4B class IVb
  tubulin beta 6 class V
  tubulin beta class I
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  ubiquitin specific peptidase 7
  ubiquitin specific peptidase 9 X-linked
  WRN helicase interacting protein 1
  X-ray repair cross complementing 5
  YTH N6-methyladenosine RNA binding protein 2
  zinc finger CCCH-type containing, antiviral 1
  zinc finger protein 90

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.