MAGED2, MAGE family member D2

MAGED2, MAGE family member D2

• This gene is a member of the MAGED gene family. The MAGED genes are clustered on chromosome Xp11. This gene is located in Xp11.2, a hot spot for X-linked intellectual disability (XLID). Mutations in this gene cause a form of transient antenatal Bartter's syndrome. This gene may also be involved in several types of cancer, including breast cancer and melanoma. The protein encoded by this gene is progressively recruited from the cytoplasm to the nucleoplasm during the interphase and after nucleolar stress and is thus thought to play a role in cell cycle regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]

• Gene Synonyms (11B6, BARTS5, BCG-1, BCG1, HCA10, MAGE-D2, melanoma-associated antigen D2, MAGE-D2 antigen, breast cancer-associated gene 1 protein, hepatocellular carcinoma-associated protein JCL-1, melanoma antigen family D, 2, melanoma antigen family D2,)
• NCBI Gene ID: 10916
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UNF1
  UNIPROT ID#>>A0A024R9Y7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

MAGE family member D2 interacts with:

• 3'-phosphoadenosine 5'-phosphosulfate synthase 1
  5'-3' exoribonuclease 2
  armadillo repeat containing 6
  aurora kinase A interacting protein 1
  autophagy related 2A
  bromodomain containing 7
  centrosomal protein 250
  centrosomal protein 55
  COP9 signalosome subunit 5
  cyclin dependent kinase 20
  developmental pluripotency-associated 3
  egl-9 family hypoxia inducible factor 3
  EP300 interacting inhibitor of differentiation 1
  EP300 interacting inhibitor of differentiation 2
  EP300 interacting inhibitor of differentiation 3
  F-box and WD repeat domain containing 7
  glutamate rich WD repeat containing 1
  golgi to ER traffic protein 4
  GRB10 interacting GYF protein 2
  inturned planar cell polarity protein
  kinase suppressor of ras 1
  limb development membrane protein 1 like
  methylphosphate capping enzyme
  MMS19 homolog, cytosolic iron-sulfur assembly component
  nicastrin
  NSE4 homolog A, SMC5-SMC6 complex component
  opioid growth factor receptor
  OTU deubiquitinase, ubiquitin aldehyde binding 1
  pleckstrin homology domain containing A4
  PR/SET domain 16
  protein phosphatase 4, catalytic subunit
  PTEN induced kinase 1
  RAD18 E3 ubiquitin protein ligase
  RIC8 guanine nucleotide exchange factor B
  RNA polymerase II associated protein 1
  serrate, RNA effector molecule
  SNW domain containing 1
  solute carrier family 6 (neurotransmitter transporter, creatine), member 8
  SprT-like N-terminal domain
  testin LIM domain protein
  tigger transposable element derived 6
  timeless interacting protein
  translocase of outer mitochondrial membrane 22
  transmembrane protein 63B
  trimethylguanosine synthase 1
  tripartite motif containing 11
  tubulin alpha 1c
  tubulin beta class I
  tubulin polyglutamylase complex subunit 1
  vir like m6A methyltransferase associated
  WW domain containing E3 ubiquitin protein ligase 2
  zinc finger and BTB domain containing 38
  zinc finger and BTB domain containing 7A
  zinc finger protein 281
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.