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SRSF2, serine and arginine rich splicing factor 2

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SRSF2, serine and arginine rich splicing factor 2

  • The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11. [provided by RefSeq, Sep 2010]

  • Gene Synonyms (serine/arginine-rich splicing factor 2, SR splicing factor 2, splicing component, 35 kDa, splicing factor SC35, splicing factor, arginine/serine-rich 2, PR264, SC-35, SC35, SFRS2, SFRS2A, SRp30b,)
  • NCBI Gene ID: 6427
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>Q01130
    UNIPROT ID#>>Q53FN0
    UNIPROT ID#>>A0A024R8U5
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

serine and arginine rich splicing factor 2 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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