PDCD4, programmed cell death 4

PDCD4, programmed cell death 4

• This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

• Gene Synonyms (programmed cell death protein 4, neoplastic transformation inhibitor protein, nuclear antigen H731, programmed cell death 4 (neoplastic transformation inhibitor), protein 197/15a, H731,)
• NCBI Gene ID: 27250
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DKX4
  UNIPROT ID#>>Q53EL6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

programmed cell death 4 interacts with:

• catechol-O-methyltransferase domain containing 1
  centrosomal protein 19
  denticleless E3 ubiquitin protein ligase homolog
  DExD/H-box helicase 60
  immunoglobulin superfamily member 8
  leucine rich repeat kinase 1
  PCF11 cleavage and polyadenylation factor subunit
  programmed cell death 4
  TGFB induced factor homeobox 2 like Y-linked
  THO complex 2
  transmembrane protein 51
  ubiquitin conjugating enzyme E2 S
  unk zinc finger

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.