LRRK1, leucine rich repeat kinase 1

LRRK1, leucine rich repeat kinase 1

• This gene encodes a multi-domain protein that is a leucine-rich repeat kinase and a GDP/GTP binding protein. The encoded protein is thought to play a role in the regulation of bone mass. Mice lacking a similar gene showed severe osteopetrosis, increased bone mineralization and decreased bone resorption. [provided by RefSeq, Jan 2017]

• Gene Synonyms (leucine-rich repeat serine/threonine-protein kinase 1, RIPK6, Roco1,)
• NCBI Gene ID: 79705
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q38SD2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

leucine rich repeat kinase 1 interacts with:

• chromosome 11 open reading frame 52
  chromosome 9 open reading frame 163
  clavesin 1
  complexin 3
  docking protein 3
  enkurin, TRPC channel interacting protein
  F-box and leucine rich repeat protein 14
  itchy E3 ubiquitin protein ligase
  leucine rich repeat kinase 1
  leucine rich repeat kinase 2
  mitochondrial ribosome associated GTPase 1
  nudix hydrolase 16 like 1
  RNA polymerase II subunit M
  sorting nexin family member 21
  testis expressed 33
  TIR domain containing adaptor protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.