SLC3A2, solute carrier family 3 member 2

SLC3A2, solute carrier family 3 member 2

• This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized. [provided by RefSeq, Nov 2010]

• Gene Synonyms (4F2 cell-surface antigen heavy chain, CD98 heavy chain, antigen defined by monoclonal antibody 4F2, heavy chain, antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43, lymphocyte activation antigen 4F2 large subunit, monoclonal antibody 44D7, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2, solute carrier family 3 (amino acid transporter heavy chain), member 2, 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE,)
• NCBI Gene ID: 6520
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P08195
  UNIPROT ID#>>J3KPF3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

solute carrier family 3 member 2 interacts with:

• AAR2 splicing factor
  ankyrin repeat and SOCS box containing 11
  ankyrin repeat and SOCS box containing 5
  anterior gradient 2, protein disulphide isomerase family member
  apoptotic chromatin condensation inducer 1
  armadillo repeat containing 8
  Bet1 golgi vesicular membrane trafficking protein
  BRF2 RNA polymerase III transcription initiation factor subunit
  cell division cycle 73
  coiled-coil domain containing 8
  CTD small phosphatase like
  cullin 3
  cullin 7
  cytochrome b5 type B
  developmental pluripotency-associated 3
  dual specificity phosphatase 12
  dual specificity phosphatase 23
  EBP cholestenol delta-isomerase
  egl-9 family hypoxia inducible factor 3
  elongation factor Tu GTP binding domain containing 2
  elongin B
  eukaryotic translation initiation factor 3 subunit I
  glutathione S-transferase kappa 1
  HEXIM P-TEFb complex subunit 1
  integrin alpha FG-GAP repeat containing 1
  interferon induced transmembrane protein 3
  itchy E3 ubiquitin protein ligase
  leucine rich repeat containing G protein-coupled receptor 4
  limb development membrane protein 1 like
  membrane bound O-acyltransferase domain containing 1
  methyltransferase like 14
  mitochondrial ribosomal protein S9
  mitotic arrest deficient 2 like 2
  MMS19 homolog, cytosolic iron-sulfur assembly component
  myotubularin related protein 7
  OTU deubiquitinase, ubiquitin aldehyde binding 1
  PIH1 domain containing 1
  PR/SET domain 16
  pre-mRNA processing factor 8
  PTEN induced kinase 1
  RAB9A, member RAS oncogene family
  RAD18 E3 ubiquitin protein ligase
  RecQ like helicase 4
  rhomboid 5 homolog 2
  serine/threonine/tyrosine interacting like 1
  solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
  solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
  solute carrier family 7 member 10
  solute carrier family 7 member 11
  solute carrier family 7 member 5
  solute carrier family 7 member 7
  solute carrier family 7 member 8
  sterol O-acyltransferase 1
  testin LIM domain protein
  thioredoxin interacting protein
  thymopoietin
  TLC domain containing 3A
  trans-golgi network protein 2
  transmembrane protein 17
  transmembrane protein 216
  tripartite motif containing 14
  tripartite motif containing 25
  U2 small nuclear RNA auxiliary factor 2
  ubiquilin 2
  valosin containing protein
  vesicle associated membrane protein 3
  vir like m6A methyltransferase associated
  voltage dependent anion channel 1
  von Hippel-Lindau tumor suppressor
  WW domain containing oxidoreductase
  zinc finger CCCH-type containing 18
  zinc finger protein 598, E3 ubiquitin ligase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.