BRF2, BRF2 RNA polymerase III transcription initiation factor subunit

BRF2, BRF2 RNA polymerase III transcription initiation factor subunit

• This gene encodes one of the multiple subunits of the RNA polymerase III transcription factor complex required for transcription of genes with promoter elements upstream of the initiation site. The product of this gene, a TFIIB-like factor, is directly recruited to the TATA-box of polymerase III small nuclear RNA gene promoters through its interaction with the TATA-binding protein. [provided by RefSeq, Jul 2008]

• Gene Synonyms (BRFU, TFIIIB50, transcription factor IIIB 50 kDa subunit, B-related factor 2, BRF-2, BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit, BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like, RNA polymerase III transcription initiation factor BRFU, hBRFU, hTFIIIB50, transcription factor IIB- related factor, TFIIIB50,)
• NCBI Gene ID: 55290
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9HAW0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

BRF2 RNA polymerase III transcription initiation factor subunit interacts with:

• exportin 4
  importin 4
  ORC ubiquitin ligase 1
  small ArfGAP 1
  sphingomyelin phosphodiesterase 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.