CKB, creatine kinase B

CKB, creatine kinase B

• The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]

• Gene Synonyms (creatine kinase B-type, brain creatine kinase, creatine kinase B chain, creatine kinase brain, creatine kinase brain-type, creatine phosphokinase B-type, epididymis luminal protein 211, epididymis secretory protein Li 29, B-CK, BCK, CKBB, CPK-B, HEL-211, HEL-S-29,)
• NCBI Gene ID: 1152
• Species: Homo sapiens (Human)
• UNIPROT ID#>>V9HWH2
  UNIPROT ID#>>P12277
  UNIPROT ID#>>G3V4N7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

creatine kinase B interacts with:

• ACD shelterin complex subunit and telomerase recruitment factor
  agrin
  aminopeptidase puromycin sensitive
  ankyrin repeat and SOCS box containing 12
  ankyrin repeat and SOCS box containing 16
  ankyrin repeat and SOCS box containing 9
  ariadne RBR E3 ubiquitin protein ligase 2
  armadillo repeat containing 8
  ataxin 3
  B9 domain containing 2
  carnosine dipeptidase 2
  centriolin
  centrobin, centriole duplication and spindle assembly protein
  centromere protein J
  centrosomal protein 120
  chromosome segregation 1 like
  coiled-coil domain containing 8
  creatine kinase, M-type
  cullin 1
  cullin 3
  cullin 7
  DDB1 and CUL4 associated factor 15
  DEAD-box helicase 10
  dihydrolipoamide dehydrogenase
  dihydrolipoamide S-succinyltransferase
  DNA fragmentation factor subunit alpha
  dual specificity phosphatase 19
  dynamin 1 like
  endoplasmic reticulum protein 44
  eukaryotic translation elongation factor 2
  FTO alpha-ketoglutarate dependent dioxygenase
  FUS RNA binding protein
  glucose-6-phosphate dehydrogenase
  golgin A2
  heat shock protein family E (Hsp10) member 1
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  HEXIM P-TEFb complex subunit 1
  high mobility group box 2
  histone deacetylase 5
  integrin linked kinase
  IQ motif containing B1
  isochorismatase domain containing 1
  keratin 17
  La ribonucleoprotein 7, transcriptional regulator
  lactate dehydrogenase B
  leucine rich repeat kinase 2
  leucine zipper like transcription regulator 1
  mitogen-activated protein kinase 13
  Mov10 RISC complex RNA helicase
  mutL homolog 1
  MYC proto-oncogene, bHLH transcription factor
  myosin heavy chain 7B
  N-acetylneuraminate synthase
  neurotrophic receptor tyrosine kinase 1
  nuclear transcription factor, X-box binding 1
  obscurin like cytoskeletal adaptor 1
  p21 (RAC1) activated kinase 2
  phosphoethanolamine/phosphocholine phosphatase 1
  phospholipase A2 group IVA
  phosphoribosylformylglycinamidine synthase
  pleckstrin homology domain containing A4
  POC1 centriolar protein A
  pre-mRNA processing factor 8
  progesterone receptor membrane component 1
  proteasome 20S subunit alpha 3
  protection of telomeres 1
  protein phosphatase 1 catalytic subunit alpha
  protein phosphatase 1 catalytic subunit gamma
  protein phosphatase 2 scaffold subunit Aalpha
  protein phosphatase targeting COQ7
  RAD52 homolog, DNA repair protein
  Ras related GTP binding B
  RecQ like helicase 4
  ring-box 1
  selenocysteine lyase
  sirtuin 7
  SLC9A3 regulator 1
  solute carrier family 15 member 3
  spindle and centriole associated protein 1
  sterol O-acyltransferase 1
  stress associated endoplasmic reticulum protein family member 2
  succinate dehydrogenase complex flavoprotein subunit A
  superoxide dismutase 1
  TAR DNA binding protein
  telomeric repeat binding factor 1
  TERF1 interacting nuclear factor 2
  TGF-beta activated kinase 1 (MAP3K7) binding protein 1
  TNFAIP3 interacting protein 2
  TRAF3 interacting protein 1
  transcription factor CP2
  transglutaminase 2
  tripartite motif containing 63
  tropomyosin 1
  tropomyosin 3
  tropomyosin 4
  tubulin folding cofactor B
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
  ubiquitin conjugating enzyme E2 M
  ubiquitin family domain containing 1
  ubiquitin specific peptidase 15
  ubiquitin specific peptidase like 1
  unc-93 homolog B1, TLR signaling regulator
  voltage dependent anion channel 1
  Yes1 associated transcriptional regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.