DUSP19, dual specificity phosphatase 19

DUSP19, dual specificity phosphatase 19

• Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]

• Gene Synonyms (DUSP17, LMWDSP3, SKRP1, TS-DSP1, dual specificity protein phosphatase 19, SAPK pathway-regulating phosphatase 1, dual specificity phosphatase TS-DSP1, low molecular weight dual specificity phosphatase 3, protein phosphatase SKRP1, stress-activated protein kinase pathway-regulating phosphatase 1,)
• NCBI Gene ID: 142679
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8WTR2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

dual specificity phosphatase 19 interacts with:

• actin beta like 2
  CUE domain containing 1
  dihydrofolate reductase 2
  dual specificity phosphatase 19
  glutamine amidotransferase like class 1 domain containing 1
  nudix hydrolase 10

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