CDC25C, cell division cycle 25C

CDC25C, cell division cycle 25C

• This gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It also suppresses p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Dec 2015]

• Gene Synonyms (M-phase inducer phosphatase 3, dual specificity phosphatase CDC25C, mitosis inducer CDC25, phosphotyrosine phosphatase, protein phosphatase 1, regulatory subunit 60, CDC25, PPP1R60,)
• NCBI Gene ID: 995
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P30307
  UNIPROT ID#>>B4DX61
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cell division cycle 25C interacts with:

• adenosylhomocysteinase like 1
  apolipoprotein L domain containing 1
  BR serine/threonine kinase 1
  BR serine/threonine kinase 2
  calmodulin regulated spectrin associated protein family member 2
  casein kinase 2 alpha 2
  CDP-diacylglycerol synthase 1
  cell division cycle 25C
  cell division cycle 37, HSP90 cochaperone
  checkpoint kinase 1
  checkpoint kinase 2
  chibby family member 1, beta catenin antagonist
  cingulin
  C-terminal binding protein 2
  cyclin B2
  cyclin dependent kinase 2
  cyclin dependent kinase 5
  cyclin-dependent kinase 1
  DENN domain containing 1A
  DENN domain containing 4C
  doublecortin like kinase 1
  dynein light chain Tctex-type 1
  epidermal growth factor receptor
  erb-b2 receptor tyrosine kinase 3
  erb-b2 receptor tyrosine kinase 4
  eukaryotic translation initiation factor 4E family member 2
  flavin adenine dinucleotide synthetase 1
  four and a half LIM domains 1
  four and a half LIM domains 2
  four and a half LIM domains 3
  glyoxalase I
  GRB10 interacting GYF protein 1
  GRB10 interacting GYF protein 2
  GrpE like 1, mitochondrial
  heat shock protein 90 alpha family class A member 1
  heat shock protein family A (Hsp70) member 4
  heat shock protein family A (Hsp70) member 4 like
  heat shock protein family D (Hsp60) member 1
  HECT and RLD domain containing E3 ubiquitin protein ligase 2
  histone deacetylase 4
  HRas proto-oncogene, GTPase
  HSPA (Hsp70) binding protein 1
  inositol polyphosphate-5-phosphatase E
  integrin linked kinase
  kinase suppressor of ras 1
  kinesin family member 13B
  kinesin family member 1C
  LCK proto-oncogene, Src family tyrosine kinase
  lemur tyrosine kinase 2
  leucine rich pentatricopeptide repeat containing
  leucine rich repeat and fibronectin type III domain containing 1
  leucine zipper tumor suppressor 1
  LIM domain and actin binding 1
  LIM domain only 1
  LIM domain only 2
  LIM domain only 3
  lipin 3
  MAPK associated protein 1
  MDM2 proto-oncogene
  membrane associated guanylate kinase, WW and PDZ domain containing 1
  microtubule affinity regulating kinase 3
  microtubule associated serine/threonine kinase 3
  mitogen-activated protein kinase 1
  mitogen-activated protein kinase 14
  mitogen-activated protein kinase 3
  mitogen-activated protein kinase 9
  mitogen-activated protein kinase kinase kinase 21
  myosin IB
  myosin IC
  NAD kinase
  NEDD4 E3 ubiquitin protein ligase
  neurofibromin 1
  neuron navigator 1
  nucleoporin 188
  nucleoporin 93
  oxysterol binding protein like 6
  peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  pleckstrin homology domain containing A4
  pleckstrin homology domain containing A7
  pleckstrin homology like domain family B member 2
  pleckstrin homology like domain family B member 3
  PNMA family member 2
  polo like kinase 1
  polo like kinase 3
  potassium channel tetramerization domain containing 3
  proliferating cell nuclear antigen
  protein kinase N1
  protein phosphatase 2 regulatory subunit Balpha
  protein phosphatase 2 regulatory subunit B''beta
  protein phosphatase 2 regulatory subunit Bdelta
  protein phosphatase 2 scaffold subunit Aalpha
  protein phosphatase, Mg2+/Mn2+ dependent 1H
  protein tyrosine phosphatase non-receptor type 13
  Ral GEF with PH domain and SH3 binding motif 2
  RAS protein activator like 2
  receptor tyrosine kinase like orphan receptor 2
  rhotekin
  ribosomal protein S27a
  S100 calcium binding protein A10
  serine and arginine rich splicing factor 12
  SH3 and PX domains 2A
  SH3 domain containing ring finger 3
  SHC adaptor protein 1
  signal induced proliferation associated 1 like 1
  sirtuin 1
  SLIT-ROBO Rho GTPase activating protein 2
  Sp1 transcription factor
  SRA stem-loop interacting RNA binding protein
  StAR related lipid transfer domain containing 13
  stratifin
  stress induced phosphoprotein 1
  SUFU negative regulator of hedgehog signaling
  synapse defective Rho GTPase homolog 1
  synthesis of cytochrome C oxidase 2
  TBCC domain containing 1
  testis associated actin remodelling kinase 2
  tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
  TIAM Rac1 associated GEF 1
  tripeptidyl peptidase 1
  tropomyosin 4
  tumor protein p53
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
  ubiquitin specific peptidase 17 like family member 2
  valyl-tRNA synthetase 1
  VPS26, retromer complex component A
  zinc finger and BTB domain containing 21
  zinc finger protein 638

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.