CBY1, chibby family member 1, beta catenin antagonist

CBY1, chibby family member 1, beta catenin antagonist

• Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (protein chibby homolog 1, ARPP-binding protein, PKD2 interactor, Golgi and endoplasmic reticulum-associated 1, chibby CTNNB1-mediated transcription inhibitor, chibby homolog 1, coiled-coil protein PIGEA-14, cytosolic leucine-rich protein, polycystin-2 interactor, Golgi- and endoplasmic reticulum-associated protein, 14 kDa, C22orf2, CBY, Chibby1, HS508I15A, PGEA1, PIGEA-14, PIGEA14, arb1,)
• NCBI Gene ID: 25776
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R1L9
  UNIPROT ID#>>Q9Y3M2
  UNIPROT ID#>>A0A087WUW0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

chibby family member 1, beta catenin antagonist interacts with:

• actin binding transcription modulator
  AKT1 substrate 1
  ankyrin repeat domain 34A
  ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
  CBY1 interacting BAR domain containing 1
  cilia and flagella associated protein 53
  cingulin
  coiled-coil-helix-coiled-coil-helix domain containing 1
  CREB regulated transcription coactivator 2
  CREB regulated transcription coactivator 3
  CWC25 spliceosome associated protein homolog
  DAB2 interacting protein
  DAZ interacting zinc finger protein 1 like
  DEAD-box helicase 41
  decapping mRNA 1A
  decapping mRNA 1B
  dedicator of cytokinesis 7
  DENN domain containing 1A
  DENN domain containing 4C
  DEP domain containing 1B
  dishevelled binding antagonist of beta catenin 3
  DNA damage induced apoptosis suppressor
  enhancer of mRNA decapping 3
  enkurin domain containing 1
  FAM161 centrosomal protein B
  family with sequence similarity 110 member A
  family with sequence similarity 110 member B
  family with sequence similarity 122B
  family with sequence similarity 53 member C
  FYVE, RhoGEF and PH domain containing 6
  ganglioside induced differentiation associated protein 2
  golgi reassembly stacking protein 2
  GRB10 interacting GYF protein 1
  GRB10 interacting GYF protein 2
  histone deacetylase 7
  inositol polyphosphate-5-phosphatase E
  kinesin light chain 3
  kinesin light chain 4
  leucine rich repeat and fibronectin type III domain containing 1
  leucine rich repeats and calponin homology domain containing 2
  ligand of numb-protein X 1
  LIM domain and actin binding 1
  lipin 3
  MAP7 domain containing 3
  MAPK associated protein 1
  MICAL like 1
  mitochondrial fission regulator 1 like
  mitogen-activated protein kinase kinase kinase 21
  NAD kinase
  NBPF member 11
  neuron navigator 1
  NFKB activating protein
  olfactomedin 2
  oxysterol binding protein like 3
  oxysterol binding protein like 6
  pantothenate kinase 2
  PDZ domain containing 11
  pleckstrin homology domain containing A5
  pleckstrin homology domain containing A7
  pleckstrin homology like domain family B member 2
  potassium channel tetramerization domain containing 3
  protein phosphatase, Mg2+/Mn2+ dependent 1H
  RAB11 family interacting protein 1
  RAB3A interacting protein
  Ral GEF with PH domain and SH3 binding motif 2
  Ras association domain family member 10
  receptor accessory protein 3
  receptor accessory protein 4
  regulatory associated protein of MTOR complex 1
  Rho GTPase activating protein 19
  serine and arginine rich splicing factor 12
  SH3 domain containing ring finger 3
  signal induced proliferation associated 1 like 1
  spire type actin nucleation factor 1
  StAR related lipid transfer domain containing 13
  synapse defective Rho GTPase homolog 1
  tetratricopeptide repeat domain 23 like
  tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
  TNF alpha induced protein 8 like 3
  TNFAIP3 interacting protein 2
  ubiquitin specific peptidase 21
  UHRF1 binding protein 1
  zinc finger and BTB domain containing 21
  zinc finger protein 638

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.