EDC3, enhancer of mRNA decapping 3

EDC3, enhancer of mRNA decapping 3

• This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability. [provided by RefSeq, May 2017]

• Gene Synonyms (enhancer of mRNA-decapping protein 3, LSM16 homolog (EDC3, S. cerevisiae), enhancer of mRNA decapping 3 homolog, yjeF N-terminal domain-containing protein 2, yjeF domain containing, yjeF domain-containing protein 1, LSM16, MRT50, YJDC, YJEFN2, hYjeF_N2-15q23,)
• NCBI Gene ID: 80153
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96F86
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

enhancer of mRNA decapping 3 interacts with:

• ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
  centrosomal protein 19
  decapping mRNA 1B
  decapping mRNA 2
  EF-hand domain containing 2
  egl-9 family hypoxia inducible factor 3
  enhancer of mRNA decapping 3
  enhancer of mRNA decapping 4
  ligand of numb-protein X 1
  protein phosphatase 1 regulatory subunit 35
  RAB3A interacting protein
  serine and arginine rich splicing factor 12
  synapse defective Rho GTPase homolog 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.