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DNA-Dependent Protein Kinase Peptide Substrate

V5671_DNA-Dependent-Protein-Kinase-Peptide-Sub_3

Highly Specific Substrate for DNA-PK

  • Supplied at 10mg/ml in water
  • Km value for peptide is 760μM

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Catalog number selected: V5671

$ 272.00
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This product is discontinued
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DNA-Dependent Protein Kinase Peptide Substrate
1mg
$ 272.00
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DNA-Dependent Protein Kinase Peptide Substrate

DNA-Dependent Protein Kinase (DNA-PK) Peptide Substrate is a highly specific substrate for DNA-PK, with the sequence Glu-Pro-Pro-Leu-Ser-Gln-Glu-Ala-Phe-Ala-Asp-Leu-Trp-Lys-Lys. The Km value for this peptide is 760μM. DNA-PK is a nuclear serine/threonine protein kinase that, when activated by DNA, phosphorylates several DNA-binding substrates, including the tumor suppressor protein p53, the simian virus 40 (SV40) large T antigen and several transcription factors (e.g., SP1, OCT-1, c-Fos and serum response factor).

Properties:

  • Concentration: 10mg/ml in water at neutral pH.
  • Molecular Weight: 1,759Da.
  • Peptide Content: ≥70%. The mass of the peptide is verified by FAB/MS.

Reference:

  1. Lees-Miller, S.P. et al. (1992) Mol. Cell. Biol. 12, 5041–9.

Specifications

What's in the box?

Item Part # Size

DNA-Dependent Protein Kinase Substrate

V567A 1 × 1mg

Certificate of Analysis

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Use Restrictions

For Research Use Only. Not for Use in Diagnostic Procedures.

Storage Conditions

BB

Store at –20°C.

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