AURKB, aurora kinase B

AURKB, aurora kinase B

• This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]

• Gene Synonyms (aurora kinase B, aurora kinase B-Sv1, aurora kinase B-Sv2, aurora- and Ipl1-like midbody-associated protein 1, aurora-1, aurora-B, aurora-related kinase 2, aurora/IPL1-related kinase 2, protein phosphatase 1, regulatory subunit 48, serine/threonine kinase 12, serine/threonine-protein kinase 12, serine/threonine-protein kinase 5, serine/threonine-protein kinase aurora-B, AIK2, AIM-1, AIM1, ARK-2, ARK2, AurB, IPL1, PPP1R48, STK-1, STK12, STK5, aurkb-sv1, aurkb-sv2,)
• NCBI Gene ID: 9212
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96GD4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

aurora kinase B interacts with:

• ajuba LIM protein
  angiomotin
  ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1
  ankyrin repeat domain 17
  aurora kinase B
  aurora kinase B
  BCL2 like 11
  BTB and CNC homology 1, basic leucine zipper transcription factor 1
  calcium and integrin binding 1
  cell division cycle 37, HSP90 cochaperone
  cell division cycle 73
  cell division cycle associated 5
  cell division cycle associated 8
  cell division cycle associated 8
  centriolin
  centrosomal protein 131
  centrosomal protein 152
  centrosomal protein 170
  centrosomal protein 192
  chromobox 3
  chromobox 5
  clathrin interactor 1
  coiled-coil domain containing 8
  cullin 7
  DEAD-box helicase 24
  DEAD-box helicase 54
  DEAH-box helicase 37
  dedicator of cytokinesis 7
  defective in cullin neddylation 1 domain containing 1
  denticleless E3 ubiquitin protein ligase homolog
  egl-9 family hypoxia inducible factor 3
  eukaryotic translation initiation factor 4E nuclear import factor 1
  F-box and leucine rich repeat protein 2
  F-box and WD repeat domain containing 7
  fizzy and cell division cycle 20 related 1
  flotillin 1
  FtsJ RNA 2'-O-methyltransferase 3
  general transcription factor IIIC subunit 3
  GRB10 interacting GYF protein 2
  GrpE like 1, mitochondrial
  GTP binding protein 4
  H3 clustered histone 14
  HECT domain E3 ubiquitin protein ligase 1
  histone deacetylase 5
  histone H3 associated protein kinase
  HMG-box transcription factor 1
  hypoxia up-regulated 1
  inner centromere protein
  kelch like family member 13
  kelch like family member 21
  kelch like family member 9
  kinesin family member 20A
  LanC like 1
  large tumor suppressor kinase 2
  leucine rich pentatricopeptide repeat containing
  leucine rich repeat kinase 2
  ligand of numb-protein X 1
  limb development membrane protein 1 like
  Ly1 antibody reactive
  malignant fibrous histiocytoma amplified sequence 1
  MIA SH3 domain ER export factor 3
  microtubule associated protein 9
  microtubule associated protein RP/EB family member 1
  microtubule associated protein RP/EB family member 2
  microtubule associated protein RP/EB family member 3
  mitochondrial calcium uptake 1
  mitochondrial ribosomal protein S27
  MYB binding protein 1a
  myosin heavy chain 14
  N-acetyltransferase 10
  NDC80 kinetochore complex component
  NIM1 serine/threonine protein kinase
  ninein like
  NOC2 like nucleolar associated transcriptional repressor
  non-SMC condensin I complex subunit H
  NOP2/Sun RNA methyltransferase 2
  NSL1 component of MIS12 kinetochore complex
  nucleoporin 205
  NUF2 component of NDC80 kinetochore complex
  pleckstrin homology domain containing A4
  pleckstrin homology domain containing A5
  proline rich coiled-coil 2C
  protein phosphatase 1 regulatory subunit 13 like
  pumilio RNA binding family member 1
  Rac GTPase activating protein 1
  Ras association domain family member 1
  receptor for activated C kinase 1
  receptor interacting serine/threonine kinase 4
  regulator of chromosome condensation 2
  replication timing regulatory factor 1
  ribonucleoprotein, PTB binding 1
  ribosomal RNA processing 12 homolog
  ring finger and CCCH-type domains 2
  RNA binding motif protein 12B
  RNA binding motif protein 28
  SEC16 homolog A, endoplasmic reticulum export factor
  SERPINE1 mRNA binding protein 1
  SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
  SHANK associated RH domain interactor
  shugoshin 1
  signal recognition particle 72
  SNW domain containing 1
  spindle and kinetochore associated complex subunit 1
  spindle and kinetochore associated complex subunit 3
  SURP and G-patch domain containing 2
  SUZ12 polycomb repressive complex 2 subunit
  TBC1 domain family member 4
  TPX2 microtubule nucleation factor
  trafficking from ER to golgi regulator
  transcription elongation factor A like 4
  transducin beta like 3
  tripartite motif containing 28
  tubulin alpha 1c
  tubulin beta class I
  ubiquitin associated and SH3 domain containing B
  ubiquitin protein ligase E3 component n-recognin 4
  ubiquitin protein ligase E3 component n-recognin 5
  ubiquitin specific peptidase 35
  ZFP30 zinc finger protein
  zinc finger CCCH-type containing, antiviral 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.