RCC2, regulator of chromosome condensation 2

RCC2, regulator of chromosome condensation 2

• The protein encoded by this gene is a guanine exchange factor that is active on RalA, a small GTPase. The encoded protein and RalA are both essential for proper kinetochore-microtubule function in early mitosis. This protein has been shown to be a biomarker for colorectal cancer. [provided by RefSeq, Oct 2016]

• Gene Synonyms (TD-60, protein RCC2, RCC1-like protein TD-60, epididymis secretory sperm binding protein, telophase disk protein of 60 kDa,)
• NCBI Gene ID: 55920
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9P258
  UNIPROT ID#>>A0A024RAC5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

regulator of chromosome condensation 2 interacts with:

• coiled-coil domain containing 8
  dedicator of cytokinesis 11
  dual specificity phosphatase 29
  integrator complex subunit 14
  neutrophil cytosolic factor 1
  OTU deubiquitinase, ubiquitin aldehyde binding 2
  pleckstrin homology domain containing A4
  potassium channel modulatory factor 1
  RAD18 E3 ubiquitin protein ligase
  ribosomal protein L35
  ring finger and CCCH-type domains 1
  RIO kinase 1
  zinc finger and BTB domain containing 38

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.