HELZ, helicase with zinc finger

HELZ, helicase with zinc finger

• HELZ is a member of the superfamily I class of RNA helicases. RNA helicases alter the conformation of RNA by unwinding double-stranded regions, thereby altering the biologic activity of the RNA molecule and regulating access to other proteins (Wagner et al., 1999 [PubMed 10471385]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (probable helicase with zinc finger domain, down-regulated in human cancers protein, helicase with zinc finger domain, DHRC, DRHC, HUMORF5,)
• NCBI Gene ID: 9931
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R8K8
  UNIPROT ID#>>P42694
  UNIPROT ID#>>B7ZLW2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

helicase with zinc finger interacts with:

• AT-rich interaction domain 3B
  chitinase acidic
  chromosome 15 open reading frame 39
  chymotrypsin like elastase 3A
  CLK4 associating serine/arginine rich protein
  cyclin J like
  dual specificity phosphatase 18
  EBF transcription factor 3
  ECSIT signaling integrator
  egl-9 family hypoxia inducible factor 3
  epithelial splicing regulatory protein 1
  eukaryotic translation initiation factor 4E nuclear import factor 1
  F-box and leucine rich repeat protein 19
  F-box and WD repeat domain containing 11
  fibrosin
  G3BP stress granule assembly factor 1
  host cell factor C2
  kelch like family member 20
  KIAA1671
  lectin, galactoside-binding, soluble, 3 binding protein
  nischarin
  nuclear RNA export factor 1
  nuclear RNA export factor 2
  nucleoporin 50
  phosphatidylinositol glycan anchor biosynthesis class T
  pleckstrin homology domain containing A4
  poly(A) specific ribonuclease subunit PAN3
  polycomb group ring finger 3
  polycomb group ring finger 5
  POM121 transmembrane nucleoporin C
  RCC1 and BTB domain containing protein 1
  receptor for activated C kinase 1
  regulatory associated protein of MTOR complex 1
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  RNA binding fox-1 homolog 2
  salvador family WW domain containing protein 1
  SET and MYND domain containing 3
  SH3 and SYLF domain containing 1
  sirtuin 7
  sosondowah ankyrin repeat domain family member A
  TAR DNA binding protein
  thrombospondin type 1 domain containing 4
  TNFAIP3 interacting protein 2
  vir like m6A methyltransferase associated
  zinc finger CCCH-type containing 7A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.