DUSP18, dual specificity phosphatase 18

DUSP18, dual specificity phosphatase 18

• Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP18 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]

• Gene Synonyms (dual specificity protein phosphatase 18, low molecular weight dual specificity phosphatase 20, DSP18, DUSP20, LMWDSP20,)
• NCBI Gene ID: 150290
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8NEJ0
  UNIPROT ID#>>F2Z2P2
  UNIPROT ID#>>A0A024R1L2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

dual specificity phosphatase 18 interacts with:

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