FBXL19, F-box and leucine rich repeat protein 19

FBXL19, F-box and leucine rich repeat protein 19

• This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

• Gene Synonyms (F-box/LRR-repeat protein 19, jumonji C domain-containing histone demethylase 1C, CXXC11, Fbl19, JHDM1C,)
• NCBI Gene ID: 54620
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6PCT2
  UNIPROT ID#>>H3BVB1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

F-box and leucine rich repeat protein 19 interacts with:

• DENN domain containing 2D
  diacylglycerol O-acyltransferase 2 like 6
  EF-hand domain containing 2
  inner membrane protein, mitochondrial
  regulator of chromosome condensation 1
  reprimo, TP53 dependent G2 arrest mediator homolog
  ring finger protein 20
  STE20 related adaptor alpha
  transmembrane protein 239

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.