OIP5, Opa interacting protein 5

OIP5, Opa interacting protein 5

• The protein encoded by this gene localizes to centromeres, where it is essential for recruitment of CENP-A through the mediator Holliday junction recognition protein. Expression of this gene is upregulated in several cancers, making it a putative therapeutic target. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

• Gene Synonyms (protein Mis18-beta, LAP2alpha interactor-25, MIS18 kinetochore protein homolog B, cancer/testis antigen 86, opa-interacting protein 5, 5730547N13Rik, CT86, LINT-25, MIS18B, MIS18beta, hMIS18beta,)
• NCBI Gene ID: 11339
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O43482
  UNIPROT ID#>>A0A024R9N0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Opa interacting protein 5 interacts with:

• ABI family member 3
  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
  APOBEC1 complementation factor
  biogenesis of lysosomal organelles complex 1 subunit 5
  brain expressed X-linked 2
  calcium release activated channel regulator 2A
  catenin alpha 3
  caveolae associated protein 1
  ceramide kinase
  cerebellar degeneration related protein 2 like
  chibby family member 2
  chromosome 1 open reading frame 94
  chromosome 20 open reading frame 85
  chromosome 21 open reading frame 91
  chromosome 7 open reading frame 31
  chromosome 7 open reading frame 57
  chromosome 9 open reading frame 16
  coiled-coil alpha-helical rod protein 1
  coiled-coil domain containing 22
  coiled-coil domain containing 24
  coiled-coil domain containing 93
  coiled-coil-helix-coiled-coil-helix domain containing 2
  CUE domain containing 1
  deltex E3 ubiquitin ligase 2
  doublesex and mab-3 related transcription factor 3
  dual specificity phosphatase 21
  dystrobrevin binding protein 1
  EF-hand domain containing 1
  eukaryotic translation initiation factor 4E nuclear import factor 1
  FAM161 centrosomal protein B
  family with sequence similarity 222 member B
  fibronectin type III and SPRY domain containing 2
  GADD45G interacting protein 1
  GLIS family zinc finger 2
  GRIP and coiled-coil domain containing 1
  GRIP1 associated protein 1
  HAUS augmin like complex subunit 6
  Holliday junction recognition protein
  hyaluronan and proteoglycan link protein 2
  inhibitor of growth family member 4
  inhibitor of growth family member 5
  kelch like family member 38
  kelch like family member 42
  keratin 27
  keratin 40
  keratin associated protein 13-2
  keratin associated protein 19-5
  keratin associated protein 19-6
  kinesin family member 9
  kinetochore localized astrin (SPAG5) binding protein
  KN motif and ankyrin repeat domains 2
  leukocyte receptor cluster member 1
  lysine demethylase 1A
  mediator complex subunit 29
  mediator complex subunit 4
  migration and invasion inhibitory protein
  MIS18 binding protein 1
  MIS18 kinetochore protein A
  mitotic spindle positioning
  MORN repeat containing 3
  myelin expression factor 2
  myosin VIIA and Rab interacting protein
  NCK associated protein 5 like
  non-SMC condensin II complex subunit H2
  N-terminal EF-hand calcium binding protein 2
  nucleoporin 54
  nucleoporin 62
  NUF2 component of NDC80 kinetochore complex
  Opa interacting protein 5
  PDZ domain containing ring finger 3
  PH domain containing endocytic trafficking adaptor 1
  PHD finger protein 21A
  pleckstrin homology like domain family B member 3
  POZ/BTB and AT hook containing zinc finger 1
  proline rich 35
  prolyl 4-hydroxylase subunit alpha 3
  protein kinase N3
  protein phosphatase 1 regulatory subunit 32
  RAB guanine nucleotide exchange factor 1
  RAB26, member RAS oncogene family
  regulation of nuclear pre-mRNA domain containing 1A
  REST corepressor 1
  RIB43A domain with coiled-coils 1
  RUN and SH3 domain containing 1
  S100 calcium binding protein Z
  shisa family member 6
  small nuclear ribonucleoprotein U11/U12 subunit 25
  spermatogenesis and oogenesis specific basic helix-loop-helix 1
  spermatogenesis associated 24
  stabilizer of axonemal microtubules 1
  sterile alpha motif domain containing 7
  synaptonemal complex central element protein 1 like
  synaptosome associated protein 47
  T cell leukemia homeobox 3
  TCF3 fusion partner
  tektin 3
  testis expressed 12
  testis specific serine kinase 3
  tetrapeptide repeat homeobox 1
  THAP domain containing 11
  TNF receptor associated factor 7
  transcription factor AP-2 delta
  tribbles pseudokinase 3
  tripartite motif containing 73
  tuftelin interacting protein 11
  ubiquitin conjugating enzyme E2 T
  ubiquitin specific peptidase 54
  USH1 protein network component harmonin binding protein 1
  VPS50 subunit of EARP/GARPII complex
  VPS53 subunit of GARP complex
  WASH complex subunit 1
  YTH N6-methyladenosine RNA binding protein 1
  zinc finger matrin-type 1
  zinc finger protein 417
  zinc finger protein 655

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.