P4HA3, prolyl 4-hydroxylase subunit alpha 3

P4HA3, prolyl 4-hydroxylase subunit alpha 3

• This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

• Gene Synonyms (prolyl 4-hydroxylase subunit alpha-3, 4-PH alpha-3, C-P4H alpha III, collagen prolyl 4-hydroxylase alpha(III), procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III, prolyl 4-hydroxylase, alpha polypeptide III,)
• NCBI Gene ID: 283208
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q7Z4N8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

prolyl 4-hydroxylase subunit alpha 3 interacts with:

• family with sequence similarity 171 member A2
  keratin associated protein 19-5
  keratin associated protein 6-1
  keratin associated protein 8-1
  mitochondrial coiled-coil domain 1
  scavenger receptor class A member 5
  WD repeat domain 62

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.