APPBP2, amyloid beta precursor protein binding protein 2

APPBP2, amyloid beta precursor protein binding protein 2

• The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

• Gene Synonyms (APP-BP2, HS.84084, PAT1, amyloid protein-binding protein 2, amyloid beta precursor protein (cytoplasmic tail) binding protein 2, protein interacting with APP tail 1,)
• NCBI Gene ID: 10513
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q92624
  UNIPROT ID#>>A0A024QZ47
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

amyloid beta precursor protein binding protein 2 interacts with:

• adaptor related protein complex 4 subunit sigma 1
  adenylate kinase 3
  aldehyde dehydrogenase 1 family member L1
  alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
  amyloid beta precursor protein binding protein 2
  ankyrin repeat domain 10
  ariadne RBR E3 ubiquitin protein ligase 1
  armadillo repeat containing X-linked 5
  ATPase 13A1
  bridging integrator 2
  C1q and TNF related 2
  CBY1 interacting BAR domain containing 1
  charged multivesicular body protein 5
  chromosome 1 open reading frame 50
  chromosome 6 open reading frame 226
  coiled-coil domain containing 167
  coiled-coil domain containing 85C
  collagen type XXIV alpha 1 chain
  COP9 signalosome subunit 6
  COP9 signalosome subunit 7B
  COP9 signalosome subunit 8
  CST telomere replication complex component 1
  cyclic GMP-AMP synthase
  cyclin L1
  DEAQ-box RNA dependent ATPase 1
  dedicator of cytokinesis 8
  dermcidin
  dolichol kinase
  endoplasmic reticulum oxidoreductase 1 alpha
  EP300 interacting inhibitor of differentiation 3
  family with sequence similarity 107 member A
  F-box and leucine rich repeat protein 5
  follistatin like 1
  FXYD domain containing ion transport regulator 7
  G protein-coupled receptor class C group 5 member C
  GATA zinc finger domain containing 2A
  germinal center associated signaling and motility
  glomulin, FKBP associated protein
  homeodomain interacting protein kinase 4
  hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
  inturned planar cell polarity protein
  kelch like family member 35
  kelch repeat and BTB domain containing 7
  kinesin family member 6
  LanC like 2
  leucine zipper protein 4
  LON peptidase N-terminal domain and ring finger 3
  LUC7 like 2, pre-mRNA splicing factor
  mago homolog, exon junction complex core component
  major facilitator superfamily domain containing 3
  mannosidase alpha class 2B member 2
  matrix metallopeptidase 28
  mitochondrial E3 ubiquitin protein ligase 1
  mucolipin 1
  NPR2 like, GATOR1 complex subunit
  patatin like phospholipase domain containing 5
  peptidylprolyl isomerase like 6
  pyridine nucleotide-disulphide oxidoreductase domain 2
  Rab interacting lysosomal protein like 1
  RAB7B, member RAS oncogene family
  Ras association domain family member 5
  Ras association domain family member 8
  ribosome biogenesis regulator 1 homolog
  ring finger protein 123
  ring finger protein 128
  ring finger protein 34
  salt inducible kinase 1
  sec1 family domain containing 1
  selenoprotein I
  selenoprotein V
  SLAIN motif family member 2
  solute carrier family 25 member 23
  solute carrier family 7 member 10
  sorting nexin 5
  speedy/RINGO cell cycle regulator family member E2
  speedy/RINGO cell cycle regulator family member E2B
  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
  synaptotagmin 11
  synergin gamma
  TAFA chemokine like family member 4
  THO complex 3
  thrombospondin type 1 domain containing 4
  transcription factor 25
  transducin beta like 3
  tRNA methyltransferase 2 homolog A
  ubiquitin conjugating enzyme E2 R2
  ubiquitin specific peptidase 25
  UDP-glucose glycoprotein glucosyltransferase 2
  WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
  WD repeat domain 24
  Wnt family member 5B
  zinc finger CCCH-type containing 10
  zinc finger CCHC-type containing 12
  zinc finger imprinted 2
  zinc finger protein 408
  zinc finger protein 747
  zinc finger protein 785

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.