RASSF5, Ras association domain family member 5

RASSF5, Ras association domain family member 5

• This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ras association domain-containing protein 5, Rap1-binding protein, Ras association (RalGDS/AF-6) domain family 5, Ras association (RalGDS/AF-6) domain family member 5, Ras effector-like protein, new ras effector 1, novel Ras effector 1, regulator for cell adhesion and polarization enriched in lymphoid tissue, tumor suppressor RASSF3, Maxp1, NORE1, NORE1A, NORE1B, RAPL, RASSF3,)
• NCBI Gene ID: 83593
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A8K5F3
  UNIPROT ID#>>Q8WWW0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Ras association domain family member 5 interacts with:

• homeodomain interacting protein kinase 1
  itchy E3 ubiquitin protein ligase
  keratin 40
  keratin associated protein 4-2
  microtubule associated protein 1 light chain 3 alpha
  MOB kinase activator 1B
  potassium channel tetramerization domain containing 12
  Ras association domain family member 5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.