UBE2R2, ubiquitin conjugating enzyme E2 R2

UBE2R2, ubiquitin conjugating enzyme E2 R2

• Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ubiquitin-conjugating enzyme E2 R2, E2 ubiquitin-conjugating enzyme R2, ubiquitin carrier protein R2, ubiquitin conjugating enzyme E2R 2, ubiquitin-conjugating enzyme E2-CDC34B, ubiquitin-conjugating enzyme UBC3B, ubiquitin-protein ligase R2, CDC34B, E2-CDC34B, UBC3B,)
• NCBI Gene ID: 54926
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q712K3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ubiquitin conjugating enzyme E2 R2 interacts with:

• basic leucine zipper ATF-like transcription factor 3
  deltex E3 ubiquitin ligase 3L
  inverted formin 2
  itchy E3 ubiquitin protein ligase
  mitochondrial E3 ubiquitin protein ligase 1
  patatin like phospholipase domain containing 2
  ring finger protein 113B
  ring finger protein 31
  SET and MYND domain containing 3
  transcription elongation factor A N-terminal and central domain containing 2
  ubiquitin conjugating enzyme E2 R2
  ubiquitin protein ligase E3 component n-recognin 7

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.