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POLE, DNA polymerase epsilon, catalytic subunit

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POLE, DNA polymerase epsilon, catalytic subunit

  • This gene encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in this gene have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature. [provided by RefSeq, Sep 2013]

  • Gene Synonyms (DNA polymerase epsilon catalytic subunit A, 3'-5' exodeoxyribonuclease, DNA polymerase II subunit A, DNA polymerase epsilon catalytic subunit protein, polymerase (DNA directed), epsilon, catalytic subunit, polymerase (DNA) epsilon, catalytic subunit, CRCS12, FILS, IMAGEI, POLE1,)
  • NCBI Gene ID: 5426
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>Q07864
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DNA polymerase epsilon, catalytic subunit interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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