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This gene encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in this gene have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature. [provided by RefSeq, Sep 2013]
The information on this page was collected from publicly accessible databases, and
is periodically updated. Promega makes no claims to accuracy, or ownership of these
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
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this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.