MED24, mediator complex subunit 24

MED24, mediator complex subunit 24

• This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (mediator of RNA polymerase II transcription subunit 24, CRSP complex subunit 4, activator-recruited cofactor 100 kDa component, cofactor required for Sp1 transcriptional activation subunit 4, cofactor required for Sp1 transcriptional activation, subunit 4, 100kDa, mediator of RNA polymerase II transcription, subunit 24 homolog, thyroid hormone receptor-associated protein 4, thyroid hormone receptor-associated protein complex 100 kDa component, vitamin D3 receptor-interacting protein complex 100 kDa component, vitamin D3 receptor-interacting protein complex component DRIP100, ARC100, CRSP100, CRSP4, DRIP100, MED5, THRAP4, TRAP100,)
• NCBI Gene ID: 9862
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75448
  UNIPROT ID#>>F5GY88
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mediator complex subunit 24 interacts with:

• autophagy related 16 like 1
  bromodomain containing 4
  cyclin dependent kinase 19
  Ewing sarcoma breakpoint region 1
  F-box and WD repeat domain containing 7
  jun B proto-oncogene
  kinesin associated protein 3
  limb development membrane protein 1 like
  mediator complex subunit 10
  mediator complex subunit 11
  mediator complex subunit 12
  mediator complex subunit 13
  mediator complex subunit 15
  mediator complex subunit 16
  mediator complex subunit 18
  mediator complex subunit 19
  mediator complex subunit 22
  mediator complex subunit 24
  mediator complex subunit 25
  mediator complex subunit 28
  mediator complex subunit 29
  mediator complex subunit 30
  mediator complex subunit 4
  mediator complex subunit 6
  mediator complex subunit 8
  mediator complex subunit 9
  membrane magnesium transporter 1
  MICOS10-NBL1 readthrough
  MIS12 kinetochore complex component
  mitochondrial contact site and cristae organizing system subunit 10
  mitochondrial ribosomal protein L22
  mitochondrial ribosomal protein L24
  mitochondrial ribosomal protein L27
  mitochondrial ribosomal protein L36
  mitochondrial ribosomal protein L42
  nuclear receptor subfamily 1 group I member 3
  pleckstrin homology domain containing A4
  protein phosphatase 4 regulatory subunit 1
  protein phosphatase 6 regulatory subunit 1
  ribosomal protein L35
  ribosomal protein S6 kinase A6
  RNA polymerase II associated protein 2
  SEH1 like nucleoporin
  STN1 subunit of CST complex
  SUN domain containing ossification factor
  trafficking protein particle complex 8
  tuftelin interacting protein 11
  zinc finger CCCH-type containing 13
  ZW10 interacting kinetochore protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.