MED25, mediator complex subunit 25

MED25, mediator complex subunit 25

• This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2. [provided by RefSeq, Apr 2010]

• Gene Synonyms (mediator of RNA polymerase II transcription subunit 25, ARC/mediator transcriptional coactivator subunit, activator interaction domain-containing protein 1, activator-recruited cofactor 92 kDa component, mediator of RNA polymerase II transcription, subunit 25 homolog, prostate-derived protein 78 kDa, ACID1, ARC92, BVSYS, CMT2B2, P78, PTOV2, TCBAP0758,)
• NCBI Gene ID: 81857
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q71SY5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mediator complex subunit 25 interacts with:

• cysteine rich tail 1
  dynein cytoplasmic 1 light intermediate chain 1
  family with sequence similarity 168 member B
  keratin associated protein 6-1
  keratin associated protein 6-3
  mediator complex subunit 10
  mediator complex subunit 19
  mediator complex subunit 25
  mediator complex subunit 8
  oxoeicosanoid receptor 1
  penta-EF-hand domain containing 1
  ubiquitin specific peptidase 54

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.