BRD4, bromodomain containing 4

BRD4, bromodomain containing 4

• The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

• Gene Synonyms (bromodomain-containing protein 4, chromosome-associated protein, mitotic chromosome-associated protein, CAP, HUNK1, HUNKI, MCAP,)
• NCBI Gene ID: 23476
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R7H8
  UNIPROT ID#>>O60885
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

bromodomain containing 4 interacts with:

• adaptor related protein complex 3 subunit mu 1
  ATPase family AAA domain containing 5
  BAR/IMD domain containing adaptor protein 2 like 1
  BRD4 interacting chromatin remodeling complex associated protein
  bromodomain containing 4
  bromodomain containing 9
  CaM kinase like vesicle associated
  checkpoint with forkhead and ring finger domains
  chromodomain helicase DNA binding protein 8
  chromosome 7 open reading frame 25
  chromosome 8 open reading frame 33
  DDB1 and CUL4 associated factor 16
  DNA methyltransferase 1 associated protein 1
  family with sequence similarity 90 member A1
  G protein signaling modulator 1
  H3 clustered histone 14
  H4 histone 16
  inhibitor of growth family member 3
  INO80 complex subunit B
  lysine acetyltransferase 8
  lysine demethylase 2B
  lysine demethylase 3A
  membrane magnesium transporter 1
  nuclear receptor binding SET domain protein 3
  pre-mRNA processing factor 40 homolog A
  protein prenyltransferase alpha subunit repeat containing 1
  RNA binding motif protein 25
  ubiquitin specific peptidase 17 like family member 2
  vir like m6A methyltransferase associated
  zinc finger CCCH-type containing 18

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.