NSD3, nuclear receptor binding SET domain protein 3

NSD3, nuclear receptor binding SET domain protein 3

• This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described. [provided by RefSeq, May 2015]

• Gene Synonyms (histone-lysine N-methyltransferase NSD3, WHSC1-like 1 isoform 9 with methyltransferase activity to lysine, Wolf-Hirschhorn syndrome candidate 1-like 1, nuclear SET domain-containing protein 3, protein whistle, KMT3F, KMT3G, WHISTLE, WHSC1L1, pp14328,)
• NCBI Gene ID: 54904
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BZ95
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nuclear receptor binding SET domain protein 3 interacts with:

• biorientation of chromosomes in cell division 1 like 1
  bromodomain containing 9
  chromodomain helicase DNA binding protein 8
  dedicator of cytokinesis 7
  GLIS family zinc finger 2
  glyoxylate reductase 1 homolog
  H3.5 histone
  lysine demethylase 1B
  nuclear receptor binding SET domain protein 3
  SH3 and cysteine rich domain 3
  zinc finger and BTB domain containing 38
  zinc finger protein 557

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.