TAF1B, TATA-box binding protein associated factor, RNA polymerase I subunit B

TAF1B, TATA-box binding protein associated factor, RNA polymerase I subunit B

• Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1-specific TAFs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]

• Gene Synonyms (TATA box-binding protein-associated factor RNA polymerase I subunit B, RNA polymerase I-specific TBP-associated factor 63 kDa, SL1, 63kD subunit, TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kD, TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa, TATA box-binding protein-associated factor 1B, TATA-box binding protein associated factor, RNA polymerase I, B, TBP-associated factor 1B, transcription initiation factor SL1/TIF-IB subunit B, MGC:9349, RAF1B, RAFI63, SL1, TAFI63,)
• NCBI Gene ID: 9014
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q53T94
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TATA-box binding protein associated factor, RNA polymerase I subunit B interacts with:

• ELL associated factor 1
  fermitin family member 3
  H3 clustered histone 14
  kinesin family member 19A
  NEDD4 like E3 ubiquitin protein ligase
  NSF attachment protein beta
  nuclear assembly factor 1 ribonucleoprotein
  nucleolar protein interacting with the FHA domain of MKI67
  ribosomal RNA processing 8
  ring-box 1
  RNA polymerase I subunit A
  RRN3 homolog, RNA polymerase I transcription factor
  TATA box binding protein
  TATA-box binding protein associated factor, RNA polymerase I subunit A
  TATA-box binding protein associated factor, RNA polymerase I subunit B
  TATA-box binding protein associated factor, RNA polymerase I subunit D
  TATA-box binding protein associated factor, RNA polymerase I, A
  TATA-box binding protein associated factor, RNA polymerase I, C
  THAP domain containing 7
  tripartite motif containing 44

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.