SCD, stearoyl-CoA desaturase

SCD, stearoyl-CoA desaturase

• This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Sep 2015]

• Gene Synonyms (acyl-CoA desaturase, delta(9)-desaturase, fatty acid desaturase, predicted protein of HQ0998, stearoyl-CoA desaturase (delta-9-desaturase), stearoyl-CoA desaturase opposite strand, FADS5, MSTP008, SCD1, SCDOS, hSCD1,)
• NCBI Gene ID: 6319
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O00767
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

stearoyl-CoA desaturase interacts with:

• anterior gradient 2, protein disulphide isomerase family member
  cAMP responsive element binding protein 3 like 1
  CD207 molecule
  ceramide synthase 4
  clusterin associated protein 1
  C-type lectin domain family 12 member B
  cytochrome b-245 chaperone 1
  ERGIC and golgi 3
  G protein-coupled receptor 152
  glutathione peroxidase 8 (putative)
  H4 clustered histone 1
  hydroxysteroid 17-beta dehydrogenase 12
  hydroxysteroid 17-beta dehydrogenase 13
  jagunal homolog 1
  major facilitator superfamily domain containing 14B
  membrane associated ring-CH-type finger 5
  mitochondrial translational initiation factor 3
  multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
  NEDD4 like E3 ubiquitin protein ligase
  NOP2/Sun RNA methyltransferase 5
  nuclear receptor subfamily 2 group C member 2
  pleckstrin homology domain containing A4
  receptor accessory protein 2
  reticulophagy regulator family member 3
  ribosomal protein L14
  SEC11 homolog C, signal peptidase complex subunit
  signal sequence receptor subunit 4
  small nuclear ribonucleoprotein U1 subunit 70
  sodium voltage-gated channel beta subunit 3
  solute carrier family 10 member 6
  solute carrier family 7 member 14
  sperm associated antigen 4
  tectonic family member 2
  tectonic family member 3
  testin LIM domain protein
  tetratricopeptide repeat domain 30B
  thioredoxin related transmembrane protein 2
  TLC domain containing 4
  translocase of inner mitochondrial membrane domain containing 1
  transmembrane protein 30B
  transmembrane serine protease 2
  trinucleotide repeat containing adaptor 6A
  ubiquinol-cytochrome c reductase core protein 2
  ubiquitin C
  vacuolar ATPase assembly factor VMA21
  valosin containing protein
  VAMP associated protein B and C

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.