UBASH3A, ubiquitin associated and SH3 domain containing A

UBASH3A, ubiquitin associated and SH3 domain containing A

• This gene encodes one of two family members belonging to the T-cell ubiquitin ligand (TULA) family. Both family members can negatively regulate T-cell signaling. This family member can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]

• Gene Synonyms (ubiquitin-associated and SH3 domain-containing protein A, T-cell ubiquitin ligand 1, T-cell ubiquitin ligand protein, cbl-interacting protein 4, suppressor of T-cell receptor signaling 2, CLIP4, STS-2, TULA, TULA-1,)
• NCBI Gene ID: 53347
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P57075
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ubiquitin associated and SH3 domain containing A interacts with:

• arrestin domain containing 1
  arrestin domain containing 3
  chromosome 9 open reading frame 24
  coiled-coil domain containing 33
  COP9 signalosome subunit 9
  deltex E3 ubiquitin ligase 3
  DNA damage inducible transcript 4 like
  family with sequence similarity 83 member A
  fatty acid desaturase 6
  golgin A6 family like 9
  ISY1-RAB43 readthrough
  keratin 39
  keratin 40
  keratinocyte proline rich protein
  leucine zipper tumor suppressor 2
  ligand of numb-protein X 1
  pleckstrin homology domain containing B2
  PNMA family member 5
  potassium channel tetramerization domain containing 1
  PR/SET domain 6
  prostate transmembrane protein, androgen induced 1
  ring finger protein 216
  SH3 domain containing ring finger 1
  shisa family member 6
  small nuclear ribonucleoprotein U11/U12 subunit 48
  Src like adaptor 2
  tektin 1
  tektin 4
  transmembrane and coiled-coil domains 2
  transmembrane protein 239
  tripartite motif containing 5
  tripartite motif containing 50
  tripartite motif containing 8
  ubiquitin associated and SH3 domain containing A
  ubiquitin associated and SH3 domain containing B
  VPS37B subunit of ESCRT-I
  zinc finger and BTB domain containing 42
  zinc finger C2HC-type containing 1C
  zinc finger protein 474
  zinc finger RANBP2-type containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.