SNF8, SNF8 subunit of ESCRT-II

SNF8, SNF8 subunit of ESCRT-II

• The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II), which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation. This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

• Gene Synonyms (vacuolar-sorting protein SNF8, EAP30 subunit of ELL complex, ELL-associated protein of 30 kDa, ESCRT-II complex subunit VPS22, SNF8, ESCRT-II complex subunit, homolog, Dot3, EAP30, VPS22,)
• NCBI Gene ID: 11267
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96H20
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SNF8 subunit of ESCRT-II interacts with:

• acyl-CoA binding domain containing 3
  cancer/testis antigen 55
  charged multivesicular body protein 6
  dihydrouridine synthase 3 like
  FA complementation group L
  glycerate kinase
  lysine demethylase 1A
  methyltransferase like 14
  NGG1 interacting factor 3 like 1
  NudC domain containing 3
  protein arginine methyltransferase 6
  Rab interacting lysosomal protein
  RNA pseudouridine synthase domain containing 2
  SNF8 subunit of ESCRT-II
  suppressor of variegation 3-9 homolog 2
  talin 2
  taxilin alpha
  tripartite motif containing 54
  ubiquitin like 7
  ubiquitin like modifier activating enzyme 6
  VAC14 component of PIKFYVE complex
  vacuolar protein sorting 25
  vacuolar protein sorting 25 homolog
  vacuolar protein sorting 36 homolog
  VPS28 subunit of ESCRT-I
  WD repeat domain 12

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.