VPS28, VPS28 subunit of ESCRT-I

VPS28, VPS28 subunit of ESCRT-I

• This gene encodes a protein subunit of the ESCRT-I complex (endosomal complexes required for transport), which functions in the transport and sorting of proteins into subcellular vesicles. This complex can also be hijacked to facilitate the budding of enveloped viruses from the cell membrane. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

• Gene Synonyms (vacuolar protein sorting-associated protein 28 homolog, ESCRT-I complex subunit VPS28, VPS28, ESCRT-I subunit, vacuolar protein sorting 28 homolog, vacuolar protein sorting 28-like protein, yeast class E protein Vps28p homolog,)
• NCBI Gene ID: 51160
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0S2Z5H5
  UNIPROT ID#>>Q9UK41
  UNIPROT ID#>>Q548N1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

VPS28 subunit of ESCRT-I interacts with:

• abhydrolase domain containing 17A, depalmitoylase
  ALG2 alpha-1,3/1,6-mannosyltransferase
  arrestin domain containing 1
  brain expressed X-linked 2
  caspase recruitment domain family member 9
  centrosomal protein 55
  centrosomal protein 57 like 1
  chromosome 22 open reading frame 23
  coenzyme Q3, methyltransferase
  coiled-coil domain containing 146
  cyclic GMP-AMP synthase
  DDB1 and CUL4 associated factor 6
  glucocorticoid induced 1
  HAUS augmin like complex subunit 8
  inhibitor of CDK, cyclin A1 interacting protein 1
  kinetochore scaffold 1
  LIM domain only 3
  MAP3K12 binding inhibitory protein 1
  multivesicular body subunit 12A
  multivesicular body subunit 12B
  NGG1 interacting factor 3 like 1
  NRDE-2, necessary for RNA interference, domain containing
  par-6 family cell polarity regulator beta
  pleckstrin homology domain containing A4
  PNMA family member 5
  Purkinje cell protein 2
  RANBP2 like and GRIP domain containing 5
  Ras association domain family member 5
  SHC adaptor protein 3
  shugoshin 2A
  solute carrier family 25 member 41
  stabilizer of axonemal microtubules 1
  syntaxin binding protein 4
  TNFAIP3 interacting protein 2
  tripartite motif containing 54
  ubiquitin associated protein 1
  ubiquitin conjugating enzyme E2 U
  USH1 protein network component harmonin binding protein 1
  vacuolar protein sorting 25 homolog
  VPS37A subunit of ESCRT-I
  VPS37B subunit of ESCRT-I
  VPS37C subunit of ESCRT-I
  VPS37D subunit of ESCRT-I

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.