NUDCD3, NudC domain containing 3

NUDCD3, NudC domain containing 3

• The product of this gene functions to maintain the stability of dynein intermediate chain. Depletion of this gene product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle microtubules, and spindle poles, and loss of gamma-tubulin from spindle poles. The protein localizes to the Golgi apparatus during interphase, and levels of the protein increase after the G1/S transition. [provided by RefSeq, Jul 2008]

• Gene Synonyms (NudCL, nudC domain-containing protein 3, NudC-like protein,)
• NCBI Gene ID: 23386
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8IVD9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

NudC domain containing 3 interacts with:

• -
  cyclin D1 binding protein 1
  defective in cullin neddylation 1 domain containing 1
  EvC ciliary complex subunit 2
  family with sequence similarity 136 member A
  glutamine rich 1
  host cell factor C2
  kelch domain containing 2
  kelch domain containing 3
  kelch domain containing 8A
  kelch like family member 12
  kelch like family member 13
  kelch like family member 14
  kelch like family member 20
  kelch like family member 22
  kelch like family member 28
  kelch like family member 29
  kelch like family member 6
  kelch like family member 9
  kelch repeat and BTB domain containing 4
  kelch repeat and BTB domain containing 6
  keratin associated protein 10-3
  keratin associated protein 10-7
  lunapark, ER junction formation factor
  MKS transition zone complex subunit 1
  nephrocystin 4
  NIMA related kinase 8
  penta-EF-hand domain containing 1
  protein kinase N3
  RAB3 GTPase activating non-catalytic protein subunit 2
  RPA1 related single stranded DNA binding protein, X-linked
  splicing factor 3b subunit 3
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.