TNFSF13B, TNF superfamily member 13b

TNFSF13B, TNF superfamily member 13b

• The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]

• Gene Synonyms (BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, TNLG7A, ZTNF4, tumor necrosis factor ligand superfamily member 13B, ApoL related ligand TALL-1, B-cell-activating factor, B-lymphocyte stimulator, Delta4 BAFF, TNF and ApoL-related leukocyte expressed ligand 1, TNF homolog that activates apoptosis, delta BAFF, dendritic cell-derived TNF-like molecule, epididymis secretory sperm binding protein, tumor necrosis factor (ligand) superfamily, member 13b, tumor necrosis factor (ligand) superfamily, member 20, tumor necrosis factor ligand 7A, tumor necrosis factor superfamily member 13b, tumor necrosis factor-like protein ZTNF4,)
• NCBI Gene ID: 10673
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0U5J7Q1
  UNIPROT ID#>>Q9Y275
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TNF superfamily member 13b interacts with:

• 2-phosphoxylose phosphatase 1
  3'(2'), 5'-bisphosphate nucleotidase 2
  ADP ribosylation factor GTPase activating protein 1
  AKT interacting protein
  ARFGEF family member 3
  arylsulfatase family member K
  basic leucine zipper and W2 domains 2
  BRCA1 associated ATM activator 1
  carbohydrate sulfotransferase 12
  cellular inhibitor of PP2A
  COPI coat complex subunit gamma 1
  cullin associated and neddylation dissociated 1
  cullin associated and neddylation dissociated 2 (putative)
  decaprenyl diphosphate synthase subunit 1
  dymeclin
  eukaryotic translation initiation factor 3 subunit K
  exocyst complex component 1
  exocyst complex component 2
  exocyst complex component 7
  exportin 4
  exportin 5
  exportin for tRNA
  family with sequence similarity 118 member A
  family with sequence similarity 160 member A2
  family with sequence similarity 160 member B1
  GCN1 activator of EIF2AK4
  gem nuclear organelle associated protein 4
  gem nuclear organelle associated protein 5
  GRAM domain containing 1A
  GRAM domain containing 1B
  HEAT repeat containing 1
  HEAT repeat containing 3
  hook microtubule tethering protein 1
  hook microtubule tethering protein 2
  hook microtubule tethering protein 3
  importin 11
  importin 9
  leucine rich repeats and immunoglobulin like domains 3
  midasin AAA ATPase 1
  mitogen-activated protein kinase kinase kinase 15
  MON2 homolog, regulator of endosome-to-Golgi trafficking
  non-SMC condensin I complex subunit G
  non-SMC condensin I complex subunit H
  non-SMC condensin II complex subunit G2
  nucleoporin 133
  nucleoporin 188
  nucleoporin 85
  PDS5 cohesin associated factor A
  RAN binding protein 6
  serum amyloid A like 1
  SRA stem-loop interacting RNA binding protein
  TBC1 domain family member 15
  tetratricopeptide repeat domain 17
  TNF receptor superfamily member 13B
  TNF receptor superfamily member 13C
  TNF superfamily member 13b
  transmembrane protein 131
  transmembrane protein 39A
  transportin 2
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.