BRAT1, BRCA1 associated ATM activator 1

BRAT1, BRCA1 associated ATM activator 1

• The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012]

• Gene Synonyms (BRCA1-associated ATM activator 1, BRCA1-associated protein required for ATM activation protein 1, HEAT repeat-containing protein C7orf27, BAAT1, C7orf27, NEDCAS, RMFSL,)
• NCBI Gene ID: 221927
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6PJG6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

BRCA1 associated ATM activator 1 interacts with:

• mesogenin 1
  P2Y receptor family member 8

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.