We believe this site might serve you best:

United States

English Continue

This country code will remain if no action is taken to change it.

Don't see your country?
Promega Corporation

CYP3A4 P450-Glo™ Assays with Luciferin-IPA: The Most Sensitive and Selective...

CYP3A4 P450-Glo™ Assays with Luciferin-IPA: The Most Sensitive and Selective Bioluminescent CYP3A4 Assay
  • Print
  • Email
  • Download PDF

Abstract

Here we introduce the newest bioluminescent substrate for cytochrome 3A4, Luciferin-IPA. This new generation substrate is a highly sensitive and selective probe for detecting CYP3A4 activity. The increased sensitivity allows the research to use less CYP3A4 enzyme. The substrate can be used to detect CYP3A4 gene induction and can be multiplexed with a cell viability assay.

Cell Notes 23, 17–19.

James J. Cali, Mary Sobol, Dongping Ma, H. Testsuo Uyeda, Poncho Meisenheimer

Promega Corporation and Promega Biosciences
Publication Date: 2009

Download Article (241 KB)

How to Cite This Article

Cali, J. J., Sobol, M., Ma, D., Uyeda, H. T. and Meisenheimer, P. CYP3A4 P450-Glo® Assays with Luciferin-IPA: The Most Sensitive and Selective Bioluminescent CYP3A4 Assay. [Internet] 2009. [cited: year, month, date]. Available from: http://www.promega.com/resources/pubhub/cellnotes/cyp3a4-p450-glo-assays-with-luciferin-ipa-the-most-sensitive-and-selective-bioluminescent-cyp3a4/

Cali, J. J., Sobol, M., Ma, D., Uyeda, H. T. and Meisenheimer, P. CYP3A4 P450-Glo® Assays with Luciferin-IPA: The Most Sensitive and Selective Bioluminescent CYP3A4 Assay. Promega Corporation Web site. http://www.promega.com/resources/pubhub/cellnotes/cyp3a4-p450-glo-assays-with-luciferin-ipa-the-most-sensitive-and-selective-bioluminescent-cyp3a4/ Updated 2009. Accessed Month Day, Year.

It appears that you have Javascript disabled. Our website requires Javascript to function correctly. For the best browsing experience, please enable Javascript.

Scientists at Your Service

Scientists at Your Service

We offer a range of services to help you succeed using Promega technologies. From product training to set up of automated systems and development of custom applications—our scientific support goes beyond the basics.

Ask us! We are here to help you.