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NanoBRET™ Target Engagement (TE) Assay measures compound binding at select target proteins in live cells, in real time.
Protein interaction assays and simple luminescence-based assays for cell viability, methyltransferase. histone deacetylase (HDAC) and sirtuin (SIRT) activities, deubiquitinating (DUB), deSUMOylating (SENP) and deneddylating (NEDP) proteases.
Kits for use in epigenetic studies evaluating methylation and gene expression. Includes methylation activity assays, DNA purification, methylation-sensitive restriction enzymes, PCR kits, reporter assays and transfection reagents.
Purify epigenetic proteins and epigenetic complexes, identify protein:protein or protein:DNA interactions, and study histone marks rapidly and efficiently.