HERC1, HECT and RLD domain containing E3 ubiquitin protein ligase family member 1

HERC1, HECT and RLD domain containing E3 ubiquitin protein ligase family member 1

• This gen encodes a member of the HERC protein family. This protein stimulates guanine nucleotide exchange on ARF1 and Rab proteins. This protein may be involved in membrane transport processes. [provided by RefSeq, Mar 2012]

• Gene Synonyms (probable E3 ubiquitin-protein ligase HERC1, HECT domain and RCC1-like domain-containing protein 1, HECT-type E3 ubiquitin transferase HERC1, guanine nucleotide exchange factor p532, hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1, MDFPMR, p532, p619,)
• NCBI Gene ID: 8925
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q15751
  UNIPROT ID#>>A0A024R5W0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 interacts with:

• chromosome 1 open reading frame 87
  coiled-coil domain containing 65
  dynamin 3
  glucosaminyl (N-acetyl) transferase 3, mucin type
  GRIP1 associated protein 1
  HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
  interferon induced protein with tetratricopeptide repeats 1B
  MIS12 kinetochore complex component
  MORC family CW-type zinc finger 1
  myosin light chain 12A
  neurogenin 3
  potassium channel modulatory factor 1
  proteasome 26S subunit, non-ATPase 14
  RAB guanine nucleotide exchange factor 1
  radial spoke head 10 homolog B2
  Rap guanine nucleotide exchange factor 5
  Rho GTPase activating protein 29
  ring finger protein 11
  SLAIN motif family, member 2
  slingshot protein phosphatase 3
  spermine oxidase
  tigger transposable element derived 6
  transcription factor Dp family member 3
  transient receptor potential cation channel subfamily C member 4 associated protein
  transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
  tubulin tyrosine ligase like 1
  ubiquitin conjugating enzyme E2 S
  ubiquitin specific peptidase 15
  ubiquitin specific peptidase 18
  unk zinc finger
  vacuolar protein sorting 36 homolog
  vir like m6A methyltransferase associated
  WD repeat and FYVE domain containing 3
  zinc finger B-box domain containing
  zinc finger protein 555
  zinc finger protein 563
  zinc finger protein 571
  zinc finger protein 610

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.