ENC1, ectodermal-neural cortex 1

ENC1, ectodermal-neural cortex 1

• This gene encodes a member of the kelch-related family of actin-binding proteins. The encoded protein plays a role in the oxidative stress response as a regulator of the transcription factor Nrf2, and expression of this gene may play a role in malignant transformation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

• Gene Synonyms (ectoderm-neural cortex protein 1, ectodermal-neural cortex 1 (with BTB domain), ectodermal-neural cortex 1 (with BTB-like domain), kelch-like 35, kelch-like family member 37, kelch-like protein 37, nuclear matrix protein NRP/B, nuclear restricted protein, BTB domain-like (brain), p53-induced gene 10 protein, tumor protein p53 inducible protein 10, CCL28, ENC-1, KLHL35, KLHL37, NRPB, PIG10, TP53I10,)
• NCBI Gene ID: 8507
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O14682
  UNIPROT ID#>>Q53XS2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ectodermal-neural cortex 1 interacts with:

• ectodermal-neural cortex 1
  F-box and leucine rich repeat protein 17
  kelch like ECH associated protein 1
  kelch like family member 25
  nucleus accumbens associated 1
  NudC domain containing 3
  perilipin 5
  ring-box 1
  sequestosome 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.