DGCR6, DiGeorge syndrome critical region gene 6

DGCR6, DiGeorge syndrome critical region gene 6

• DiGeorge syndrome, and more widely, the CATCH 22 syndrome, are associated with microdeletions in chromosomal region 22q11.2. The product of this gene shares homology with the Drosophila melanogaster gonadal protein, which participates in gonadal and germ cell development, and with the gamma-1 subunit of human laminin. This gene is a candidate for involvement in DiGeorge syndrome pathology and in schizophrenia. [provided by RefSeq, Nov 2008]

• Gene Synonyms (protein DGCR6, DiGeorge syndrome critical region protein 6,)
• NCBI Gene ID: 8214
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q14129
  UNIPROT ID#>>X5D7D2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DiGeorge syndrome critical region gene 6 interacts with:

• ADAMTS like 4
  A-kinase anchoring protein 8 like
  angiotensin II receptor associated protein
  aryl hydrocarbon receptor nuclear translocator 2
  aspartyl aminopeptidase
  Cbl proto-oncogene like 1
  centrosomal protein 126
  chibby family member 2
  chromosome 1 open reading frame 94
  chromosome 3 open reading frame 62
  coiled-coil domain containing 33
  dedicator of cytokinesis 8
  deuterosome assembly protein 1
  DLG associated protein 2
  EF-hand domain containing 2
  EGF containing fibulin extracellular matrix protein 2
  enkurin domain containing 1
  ess-2 splicing factor homolog
  Fas binding factor 1
  Gse1 coiled-coil protein
  hepatocyte growth factor-regulated tyrosine kinase substrate
  homeobox and leucine zipper encoding
  IKAROS family zinc finger 3
  interactor of HORMAD1 1
  INTS3 and NABP interacting protein
  kelch like family member 12
  keratin associated protein 12-2
  leucine zipper tumor suppressor 2
  MAP3K12 binding inhibitory protein 1
  midline 2
  mirror-image polydactyly 1
  notch 2 N-terminal like A
  N-terminal EF-hand calcium binding protein 2
  nucleoporin 54
  nucleoporin 62
  PDZ and LIM domain 7
  PR/SET domain 14
  RAB guanine nucleotide exchange factor 1
  regulatory factor X6
  RIMS binding protein 3
  sprouty RTK signaling antagonist 2
  SS18L1 subunit of BAF chromatin remodeling complex
  tubulin gamma complex associated protein 4
  tuftelin interacting protein 11
  zinc finger BED-type containing 1
  zinc finger C4H2-type containing
  zinc finger protein 398
  zinc finger protein 446

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.